Results 91 to 100 of about 68,479 (299)

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Investigating the Utility of Markers of Cortical Excitability in Schizophrenia

, 2019
Schizophrenia is an illness characterized by distributed dysfunction in numerous cortical and subcortical regions. Transcranial Magnetic Stimulation (TMS) is a promising research tool for directly examining the excitability of neural networks, a measure ...
Stolz, Erin R
core  

Evaluation of Cognition and Cortical Excitability in Huntington’s Disease

, 2018
Background: Recent advances in neurophysiological techniques have contributed to our understanding of the pathophysiology of Huntington’s disease (HD).
Kamble, Nitish, Netravathi, M., Sanjeev Jain, Jain, Sanjeev, B.C. Nagaraju, Pal, Pramod Kumar, Keshav Kumar, Abhishek Lenka, Pramod Kumar Pal, Kumar, Keshav, Nitish Kamble, M. Netravathi, V. Sowmya, Lenka, Abhishek, Venkatesh, Sowmya, Nagaraju, B.C.   +15 more
core   +1 more source

Regional personalized electrodes to select transcranial current stimulation target

Frontiers in Human Neuroscience, 2013
Rationale Personalizing transcranial stimulations promises to enhance beneficial effects for individual patients.ObjectiveTo stimulate specific cortical regions by developing a procedure to bend and position custom shaped electrodes; to probe the effects
Franca eTecchio, Andrea eCancelli, Carlo eCottone, Leo eTomasevic, Barbara eDevigus, Giancarlo eZito, Matilde eErcolani, Filippo eCarducci   +7 more
doaj   +1 more source

Cortical excitability following passive movement

Physical Therapy Research, 2018
In brain injury rehabilitation, passive movement exercises are frequently used to maintain or improve mobility and range of motion. They can also induce beneficial and sustained neuroplastic changes. Neuroimaging studies have revealed that passive movements without motor commands activate not only the primary somatosensory cortex but also the primary ...
openaire   +3 more sources

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Examining the Relationship between Aerobic Fitness and Cortical Excitability

, 2017
Because of its ability to enhance cortical excitability, aerobic exercise is receiving interest as a primer for learning and rehabilitation. Previous studies show that physical activity level influences the brain s response to exercise.
MacDonald, Monica
core  

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

Differential effect of visual motion adaption upon visual cortical excitability

, 2016
The objectives of this study were 1) to probe the effects of visual motion adaptation on early visual and V5/MT cortical excitability and 2) to investigate whether changes in cortical excitability following visual motion adaptation are related to the ...
Ahmad, H, Lubeck, AJA, Bos, JE, Arshad, Q, Van Ombergen, A, Wuyts, FL, Bronstein, AM   +6 more
core   +2 more sources