Results 101 to 110 of about 390,093 (289)

Examining the Relationship between Aerobic Fitness and Cortical Excitability

open access: yes, 2017
Because of its ability to enhance cortical excitability, aerobic exercise is receiving interest as a primer for learning and rehabilitation. Previous studies show that physical activity level influences the brain s response to exercise.
MacDonald, Monica
core   +2 more sources

Reduced intracortical inhibition and enhanced intracortical facilitation in patients with functional tremor

open access: yesBMJ Neurology Open
Background The pathophysiological mechanism underlying functional tremor (FT) has not been elucidated. Transcranial magnetic stimulation (TMS) is a non-invasive tool to explore cortical excitability in various neurological and neuropsychiatric disorders.
Juan Li   +4 more
doaj   +1 more source

Linking cortical network synchrony and excitability [PDF]

open access: yesCommunicative & Integrative Biology, 2016
Theoretical approaches based on dynamical systems theory can provide useful frameworks to guide experiments and analysis techniques when investigating cortical network activity. The notion of phase transitions between qualitatively different kinds of network dynamics has been such a framework inspiring novel approaches to neurophysiological data ...
openaire   +3 more sources

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

open access: yesAdvanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia   +4 more
wiley   +1 more source

Reduced cortico-muscular output is associated with intrinsic hypoexcitability and reduced persistent inward currents in motor cortex neurons of TDP-43Q331K ALS mice

open access: yesNeurobiology of Disease
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by spinal and cortical motor neuron loss and progressive neuromuscular decline.
Jose A. Viteri   +11 more
doaj   +1 more source

Resting state cortical electroencephalographic rhythms in covert hepatic encephalopathy and Alzheimer's disease [PDF]

open access: yes, 2013
Patients suffering from prodromal (i.e., amnestic mild cognitive impairment, aMCI) and overt Alzheimer's disease (AD) show abnormal cortical sources of resting state electroencephalographic (EEG) rhythms.
Nicola Marzano   +50 more
core   +1 more source

A Multi‐Scale Computational Framework for Evaluating Wireless Neuromodulation Feasibility via Magnetoelectric Nanoparticles

open access: yesAdvanced Science, EarlyView.
A multiscale computational framework links single‐nanoparticle magnetoelectric behavior to tissue‐level electric field distributions, integrating experimental data from nanoparticle characterization and in vitro stimulation setups. Applied to a cortical slice configuration, the framework predicts optimal MENP concentrations and stimulation parameters ...
Marta Bonato   +10 more
wiley   +1 more source

Investigating the Utility of Markers of Cortical Excitability in Schizophrenia

open access: yes, 2019
Schizophrenia is an illness characterized by distributed dysfunction in numerous cortical and subcortical regions. Transcranial Magnetic Stimulation (TMS) is a promising research tool for directly examining the excitability of neural networks, a measure ...
Stolz, Erin R
core   +1 more source

Aberrances of Cortex Excitability and Connectivity Underlying Motor Deficit in Acute Stroke

open access: yesNeural Plasticity, 2018
Purpose. This study was aimed at evaluating the motor cortical excitability and connectivity underlying the neural mechanism of motor deficit in acute stroke by the combination of functional magnetic resonance imaging (fMRI) and electrophysiological ...
Juan Du   +12 more
doaj   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

open access: yesAdvanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi   +8 more
wiley   +1 more source

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