Results 151 to 160 of about 68,657 (264)

Fenfluramine in Rett syndrome: A multidimensional clinical study

Epilepsia Open, EarlyView.
Abstract Objective Rett syndrome (RTT) is a severe neurodevelopmental disorder frequently associated with drug‐resistant epilepsy, autonomic dysfunction, respiratory abnormalities, sleep disturbances, and behavioral impairment. Fenfluramine has shown efficacy in developmental and epileptic encephalopathies and may provide broader therapeutic benefits ...
Elena Gonzalez‐Alguacil, Nuria Lamagrande Casanova, Manuel Luján Bonete, David Mansilla Lozano, Juan José García Peñas, María Ballará Petitbó, Rocío Trincado Lamuño, Verónica Cantarín‐Extremera, Raquel Díaz Conejo, César Rodríguez Sánchez, Adrián García Ron, Víctor Soto Insuga   +11 more
wiley   +1 more source

Exploring cortical excitability modulation to promote cognitive resilience in aging: an rTMS study protocol. [PDF]

Front Hum Neurosci
Di Fazio C, Scaliti E, Stanziano M, Nigri A, Demichelis G, Tamietto M, Palermo S.   +6 more
europepmc   +1 more source

Shared molecular pathways in pediatric genetic epilepsies: Insights from a single‐center cohort of 80 patients

Epilepsia Open, EarlyView.
Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functional pathways.
Laura Hecher, Mathias Woidy, Franziska Plein, Tatjana Bierhals, Leonie von Elsner, Theresia Herget, Maja Hempel, Fanny Kortüm, Lev Grinstein, Julia V. Cramer, Jessika Johannsen, Jonas Denecke   +11 more
wiley   +1 more source

Synergistic effects of action observation and object affordance on cortical excitability during BCI-triggered motor imagery in stroke: a randomized, within-subject, 2 × 2 factorial study protocol. [PDF]

Front Hum Neurosci
Su Y, Yan X, Li W, Wang Y, Wu X.
europepmc   +1 more source

The basal ganglia and the epilepsies

Epilepsia Open, EarlyView.
Abstract The basal ganglia are an evolutionarily conserved neural circuit best known for the selection and sequencing of voluntary movement. Increasing evidence, however, indicates that these structures also play an important role in regulating pathological brain states, including seizures.
Willian Lazarini‐Lopes, Logan Perry, Patrick A. Forcelli   +2 more
wiley   +1 more source

Calcitonin gene‐related peptide (CGRP) in epilepsy: Mechanistic insights from preclinical models

Epilepsia Open, EarlyView.
Abstract Calcitonin gene‐related peptide (CGRP) is a pleiotropic neuropeptide widely expressed in the central and peripheral nervous systems, with established roles in neurovascular regulation, synaptic transmission, and neuroinflammation. While CGRP has been extensively characterized in migraine pathophysiology, its role in epilepsy remains ...
Marina Romozzi, Luca Pani, Cristina Benatti, Catello Vollono, Jacopo Canonichesi, Serenella Servidei, Paolo Calabresi, Fabio Tascedda, Luigi Francesco Iannone   +8 more
wiley   +1 more source

Noradrenaline excitation of cortical neurons: A reply

Journal of Pharmacy and Pharmacology, 1972
L M, Jordan, N, Lake, W J, Phillis
openaire   +2 more sources

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Linking movement-related beta oscillations to cortical excitability, structural damage, and fatigue in multiple sclerosis. [PDF]

Brain Commun
Tatti E, Benelli A, Cinti A, Cortese R, Serbina A, Kulapurathazhe AJ, Saed S, Luchetti L, Cudeiro J, Zhang J, de Mauro A, Neri F, Stromillo ML, Baldi TL, d'Aurizio N, Battaglini M, Plantone D, Righi D, Massucco E, Giannotta A, Lomi F, Scoccia A, Lai G, Ulivelli M, Ghilardi MF, De Stefano N, Rossi S.   +26 more
europepmc   +1 more source