Results 131 to 140 of about 68,479 (299)
Transcranial Near-infrared-Stimulation as a kind of non-invasive Photobiostimulation of the cortex is able to modulate neurobiological functions without causing thermal damage.
Jakob, Anna Sophie
core +1 more source
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba +7 more
wiley +1 more source
The cell cortex plays many critical roles, including interpreting and responding to internal and external signals. One behavior which supports a cell’s ability to respond to both internal and externally-derived signaling is cortical excitability, wherein
Leslie A. Sepaniac (18008230) +2 more
core +1 more source
Electroencephalography (EEG) studies of Alzheimer’s Dementia (AD) have shown evidence of oscillatory abnormalities and cortical excitability, however, the relationship between the two and clinical symptoms of AD remain unclear.
Alhabbal, Hiba
core +1 more source
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le +8 more
wiley +1 more source
The cell cortex plays many critical roles, including interpreting and responding to internal and external signals. One behavior which supports a cell’s ability to respond to both internal and externally-derived signaling is cortical excitability, wherein
Leslie A. Sepaniac (18008230) +2 more
core +1 more source
A guide to neuromodulation in drug‐resistant epilepsy
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh +10 more
wiley +1 more source
Study and Modulation of Human Cortical Excitability with Transcranial Magnetic Stimulation
Transcranial magnetic stimulation (TMS) can be applied in different paradigms to obtain a measure of various aspects of cortical excitability. These different TMS paradigms provide information about different neurotransmitter systems, enhance our ...
Catalá, Maria D. +5 more
core +1 more source
The cell cortex plays many critical roles, including interpreting and responding to internal and external signals. One behavior which supports a cell’s ability to respond to both internal and externally-derived signaling is cortical excitability, wherein
Leslie A. Sepaniac (18008230) +2 more
core +1 more source
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca +10 more
wiley +1 more source

