Results 131 to 140 of about 68,479 (299)

Neuroplastic effects of transcranial near-infrared stimulation of different stimulation duration on the cortical excitability

open access: yes, 2018
Transcranial Near-infrared-Stimulation as a kind of non-invasive Photobiostimulation of the cortex is able to modulate neurobiological functions without causing thermal damage.
Jakob, Anna Sophie
core   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba   +7 more
wiley   +1 more source

Image2_Bring the pain: wounding reveals a transition from cortical excitability to epithelial excitability in Xenopus embryos.tif

open access: yes
The cell cortex plays many critical roles, including interpreting and responding to internal and external signals. One behavior which supports a cell’s ability to respond to both internal and externally-derived signaling is cortical excitability, wherein
Leslie A. Sepaniac (18008230)   +2 more
core   +1 more source

Resting State EEG Abnormalities in Alzheimer’s Dementia and their relationship with Cortical Excitability and Clinical Symptoms

open access: yes, 2023
Electroencephalography (EEG) studies of Alzheimer’s Dementia (AD) have shown evidence of oscillatory abnormalities and cortical excitability, however, the relationship between the two and clinical symptoms of AD remain unclear.
Alhabbal, Hiba
core   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le   +8 more
wiley   +1 more source

Image1_Bring the pain: wounding reveals a transition from cortical excitability to epithelial excitability in Xenopus embryos.tif

open access: yes
The cell cortex plays many critical roles, including interpreting and responding to internal and external signals. One behavior which supports a cell’s ability to respond to both internal and externally-derived signaling is cortical excitability, wherein
Leslie A. Sepaniac (18008230)   +2 more
core   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh   +10 more
wiley   +1 more source

Study and Modulation of Human Cortical Excitability with Transcranial Magnetic Stimulation

open access: yes, 1998
Transcranial magnetic stimulation (TMS) can be applied in different paradigms to obtain a measure of various aspects of cortical excitability. These different TMS paradigms provide information about different neurotransmitter systems, enhance our ...
Catalá, Maria D.   +5 more
core   +1 more source

Video3_Bring the pain: wounding reveals a transition from cortical excitability to epithelial excitability in Xenopus embryos.AVI

open access: yes
The cell cortex plays many critical roles, including interpreting and responding to internal and external signals. One behavior which supports a cell’s ability to respond to both internal and externally-derived signaling is cortical excitability, wherein
Leslie A. Sepaniac (18008230)   +2 more
core   +1 more source

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

open access: yesEpileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca   +10 more
wiley   +1 more source

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