Results 161 to 170 of about 390,093 (289)

Altered cortical synchronization in photosensitive idiopathic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto, Cecilia Steinwurzel, Francesco Turco, Enrica Bonanni, Roberto Cantello, Gionata Strigaro   +5 more
wiley   +1 more source

Transcranial Magnetic Stimulation Combined With Electroencephalography Analysis Suggest Time-Dependent and Region-Specific Modulation of Cortical Excitability During Acute Alcohol Intoxication. [PDF]

Alcohol Clin Exp Res (Hoboken)
Kekkonen V, Fonsén E, Kallioniemi E, Säisänen L, Tolmunen T, Könönen M, Kivimäki P, Määttä S.   +7 more
europepmc   +1 more source

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

Epilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi, John Williamson, Jhanvi Patel, Samikksha Kumar, Huayu Sun, Lucy Dang Nguyen, Katarzyna Rękawek, Ifrah Zawar, Jaideep Kapur   +8 more
wiley   +1 more source

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective.
Dongjun Guo, Lirong Han, Nicholas R. Rensing, Laura A. Jansen, Michael Wong   +4 more
wiley   +1 more source

Polarity-dependent modulation of sleep oscillations and cortical excitability in aging. [PDF]

Front Aging Neurosci
Dikici B, Malinowski R, Kordaß JB, Obermayer K, Ladenbauer J, Flöel A.   +5 more
europepmc   +1 more source

Could calcitonin gene‐related peptide inhibitors prevent status epilepticus?

Epilepsia, EarlyView.
Abstract Calcitonin gene‐related peptide (CGRP) inhibitors modulate pain and neuroinflammation, a recognized contributor to epileptogenesis and status epilepticus (SE). We examined the association between CGRP inhibitor use and SE hospitalization in epilepsy patients with comorbid migraine.
Michael Nsaka, Noor Baban, Sepideh Allahdadian, Armin Scheffler, Diana Lindner, Dagny Holle, Alain Lekoubou   +6 more
wiley   +1 more source

Cortical excitability mapping stratifies neurobiological subtypes of schizophrenia with genetic and molecular signatures. [PDF]

BMC Med
Guo S, Zhao Y, Ji X, Liu X, Li L, Guo Y, Zhang X, Xie R, Zeng J, Sun H, Lui S, Gong Q.   +11 more
europepmc   +1 more source

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia, Akash Bera, Omar Mamad, James D. Mills, Benjamin Villasana‐Salazar, Giada Lavigna, Edoardo Micotti, Manuela Conticello, Asmin Alam, Roberto Chiesa, Francesca Pagani, Roberta Frapolli, Angelo M. Lavecchia, Christodoulos Xinaris, Eleonora Aronica, Andre Altmann, Teresa Ravizza, Sanjay M. Sisodiya, David C. Henshall, Annamaria Vezzani   +19 more
wiley   +1 more source

Predicting levetiracetam neuropsychiatric adverse effects using graph‐theoretical electroencephalographic network metrics in drug‐naive focal epilepsy: A multicenter longitudinal study

Epilepsia, EarlyView.
Abstract Objective Levetiracetam (LEV) is an antiseizure medication approved for focal and generalized epilepsy. Despite its efficacy, neuropsychiatric adverse effects (NP‐AEs) may lead to treatment discontinuation. Quantitative electroencephalographic (qEEG) graph‐theoretical analysis has emerged as a valuable tool for identifying neurophysiological ...
Marco Sferruzzi, Lorenzo Ricci, Margherita Anna Grazia Matarrese, Francesca Izzi, Fabio Placidi, Biagio Maria Sancetta, Emanuele Cerulli Irelli, Patrizia Pulitano, Vincenzo Di Lazzaro, Mario Tombini, Giovanni Assenza   +10 more
wiley   +1 more source

Exploring cortical excitability modulation to promote cognitive resilience in aging: an rTMS study protocol. [PDF]

Front Hum Neurosci
Di Fazio C, Scaliti E, Stanziano M, Nigri A, Demichelis G, Tamietto M, Palermo S.   +6 more
europepmc   +1 more source