Results 181 to 190 of about 390,093 (289)

Noradrenaline excitation of cortical neurons: A reply

Journal of Pharmacy and Pharmacology, 1972
L M, Jordan, N, Lake, W J, Phillis
openaire   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

GABAergic and glutamatergic mechanisms of cortical excitability shape motor resonance during action observation as measured by transcranial magnetic stimulation. [PDF]

Front Hum Neurosci
Ragimova A, Imanaeva M, Nieto-Doval C, Vorobiova AN, Moiseeva V, Feurra M.   +5 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

The Association of EEG μ Rhythm Phase and Power with TMS-Assessed Cortical Excitability States. [PDF]

Sensors (Basel)
Mai W, Zhao X, Chen P, Zhao Y, Wang H, Wang X, Liu Z, Jin J, Yin T.   +8 more
europepmc   +1 more source

Rest‐activity patterns across development in two mouse models of autism and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash, Filip Fredlund, Jenny Wickham, My Andersson, Christine T. Ekdahl   +4 more
wiley   +1 more source

Reduced cortical excitability is associated with head impact severity and cognitive symptoms in adolescent football players. [PDF]

iScience
Yu KC, Wiesman AI, Davenport EM, Flashman LA, Urban JE, Nagarajan SS, Solingpuram Sai KK, Stitzel JD, Maldjian JA, Whitlow CT.   +9 more
europepmc   +1 more source

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

Epilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia, Jina Babanzadeh, Marcello Scala, Lorenzo Perilli, Pasquale Striano   +4 more
wiley   +1 more source

Increased cortical excitability to transcranial magnetic stimulation at the brain-tumor interface of <i>IDH1</i>-mutant gliomas. [PDF]

Neurooncol Adv
Stark A, Gorbachuk M, Machetanz K, Leao MT, Liebsch M, Wang S, Honegger J, Tatagiba M, Naros G.   +8 more
europepmc   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source