Dysregulated cortical excitability and tau phosphorylation in a β3 integrin mouse model of autism. [PDF]
Vitale C +9 more
europepmc +1 more source
Auditory gamma‐band synchronization and attentional performance in juvenile myoclonic epilepsy
Abstract Objective Cognitive difficulties in juvenile myoclonic epilepsy (JME) are part of the clinical phenotype alongside epileptic seizures; however, the underlying neurophysiological mechanisms remain unclear. Auditory steady‐state responses (ASSRs) to repetitive 40‐ and 80‐Hz stimuli are widely used measures of gamma‐band oscillations (GBOs ...
Ryo Mitoma +12 more
wiley +1 more source
Visual Neuroplasticity: Modulating Cortical Excitability with Flickering Light Stimulation. [PDF]
Ávila FJ.
europepmc +1 more source
Abstract EEG‐based connectivity analysis has emerged as a promising approach for investigating brain network dynamics in clinical epilepsy research. However, the diversity of analytical approaches, preprocessing pipelines, and reporting practices poses challenges to reproducibility and clinical translation.
Naoto Kuroda +6 more
wiley +1 more source
Impaired AIS plasticity in ankyrin-G mutant mice alters cortical excitability and behavior. [PDF]
Li M +11 more
europepmc +1 more source
Abstract Objective To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs). Method Anonymized patient data from real‐world studies/registries associated with European cenobamate EAPs were pooled.
Vicente Villanueva +25 more
wiley +1 more source
Cortical excitability and brain function in patients with insomnia: a pilot transcranial magnetic stimulation and functional near-infrared spectroscopy study. [PDF]
Luo J, Chen Q.
europepmc +1 more source
Bilateral detection, prediction, and lateralization of seizures using white matter
Abstract Objective To determine how the corpus callosum handles interhemispheric seizure propagation and to assess its potential as a strategic recording locus for state‐dependent biomarkers. Methods Epileptiform activity was induced in vitro and in vivo using 4‐aminopyridine. Propagation dynamics were examined using cross‐correlation analysis.
Nrupen Pakalapati +3 more
wiley +1 more source
Motor cortical excitability and inhibition are differentially modulated by aerobic exercise intensity. [PDF]
Harroum N +7 more
europepmc +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source

