Results 191 to 200 of about 68,479 (299)

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Impaired AIS plasticity in ankyrin-G mutant mice alters cortical excitability and behavior. [PDF]

Proc Natl Acad Sci U S A
Li M, Zhao B, Lu Z, Zhe L, Han Y, Chen Y, Wang H, Wang Y, Wu C, Zhang M, Chen K, Yang R.   +11 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Motor cortical excitability and inhibition are differentially modulated by aerobic exercise intensity. [PDF]

Cereb Cortex
Harroum N, O'Farrell A, Youssef L, Bohbot L, Maati H, Joubert M, Pageaux B, Neva JL.   +7 more
europepmc   +1 more source

Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals

Epilepsia Open, EarlyView.
Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and developmental encephalopathies. This study aimed to characterize sleep abnormalities in individuals with KCNB1‐related disorders, focusing on their prevalence, clinical manifestations, and impact on daily functioning.
Giovanna Scorrano, Delphine Breuillard, Anais Thimon, Nicole Chemaly, Rima Nabbout   +4 more
wiley   +1 more source

Spontaneous Alpha-Band Lateralization Extends Persistence of Visual Information in Iconic Memory by Modulating Cortical Excitability. [PDF]

J Neurosci
Smith PJC, Busch NA.
europepmc   +1 more source

Rest‐activity patterns across development in two mouse models of autism and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash, Filip Fredlund, Jenny Wickham, My Andersson, Christine T. Ekdahl   +4 more
wiley   +1 more source

Cortical Excitability as a Prognostic and Phenotypic Stratification Biomarker in Amyotrophic Lateral Sclerosis. [PDF]

Ann Neurol
Ranieri F, Senerchia G, Bonan L, Casali S, Cabona C, Cantone M, De Marchi F, Diamanti L, Doretti A, Fini N, Filosto M, Fortuna A, Iovino A, Iuzzolino VV, Lanza G, Lunetta C, Maderna L, Mandrioli J, Mazzini L, Musumeci G, Nuredini A, Sorarù G, Toriello A, Ticozzi N, Todisco M, Vacchiano V, Zinno L, Silani V, Rossi S, Di Lazzaro V, Dubbioso R, MND Study Group of the Italian Neurological Society (SIN) and the Neurostimulation‐Neuromodulation Study Group of the Italian Society of Clinical Neurophysiology (SINC).   +31 more
europepmc   +1 more source

Impact of cenobamate on cortical responses to transcranial magnetic stimulation in people with drug‐resistant focal epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Cenobamate (CNB) is an effective antiseizure medication, though its mechanisms of efficacy remain incompletely understood. We assessed changes in cortical responses to transcranial magnetic stimulation (TMS) following CNB treatment.
Silvano R. Gefferie, Diego Jiménez‐Jiménez, Gerhard H. Visser, Robert M. Helling, Arn M. J. M. van den Maagdenberg, Josemir W. Sander, Simona Balestrini, Roland D. Thijs   +7 more
wiley   +1 more source

A study on the effects of exercise training on cortical excitability in athletes: a meta-analysis based on TMS measurements. [PDF]

Front Psychol
Jiang X, Li L, Liu Y, Feng W.
europepmc   +1 more source