Results 11 to 20 of about 53,540 (338)

Chlorella vulgaris functional alcoholic beverage: Effect on propagation of cortical spreading depression and functional properties. [PDF]

PLoS ONE, 2021
Recent advances in microalgae biotechnology have proven that these microorganisms contain a number of bioactive molecules, that can be used as food additives that help prevent disease. The green microalga Chlorella vulgaris presents several biomolecules,
Danielli M M Dantas, Thiago B Cahú, Carlos Yure B Oliveira, Ricardo Abadie-Guedes, Nathalia A Roberto, Werlayne M Santana, Alfredo O Gálvez, Rubem C A Guedes, Ranilson S Bezerra   +8 more
doaj   +4 more sources

Migraine Visual Aura and Cortical Spreading Depression—Linking Mathematical Models to Empirical Evidence [PDF]

Vision, 2021
This review describes the subjective experience of visual aura in migraine, outlines theoretical models of this phenomenon, and explores how these may be linked to neurochemical, electrophysiological, and psychophysical differences in sensory processing ...
Louise O’Hare, Jordi M. Asher, Paul B. Hibbard   +2 more
doaj   +3 more sources

Metabolic Pathophysiology of Cortical Spreading Depression: A Review [PDF]

Brain Sciences
Cortical spreading depression (CSD) is an electrophysiologic pathological state in which a wave of depolarization in the cerebral cortex is followed by the suppression of spontaneous neuronal activity.
Arren Hill, Alfred B. Amendolara, Christina Small, Steve Cochancela Guzman, Devin Pfister, Kaitlyn McFarland, Marina Settelmayer, Scott Baker, Sean Donnelly, Andrew Payne, David Sant, John Kriak, Kyle B. Bills   +12 more
doaj   +4 more sources

Transient Global Amnesia: An Electrophysiological Disorder Based on Cortical Spreading Depression—Transient Global Amnesia Model [PDF]

Frontiers in Human Neuroscience, 2020
Transient global amnesia (TGA) is a benign memory disorder with etiologies that have been debated for a long time. The prevalence of stressful events before a TGA attack makes it hard to overlook these precipitating factors, given that stress has the ...
Xuejiao Ding, Xuejiao Ding, Dantao Peng
doaj   +3 more sources

Clinical correlates of mathematical modeling of cortical spreading depression: Single‐cases study [PDF]

Brain and Behavior, 2019
Introduction Considerable connections between migraine with aura and cortical spreading depression (CSD), a depolarization wave originating in the visual cortex and traveling toward the frontal lobe, lead to the hypothesis that CSD is underlying migraine
Julia M. Kroos, Marina deTommaso, Sebastiano Stramaglia, Eleonora Vecchio, Nicola Burdi, Luca Gerardo‐Giorda   +5 more
doaj   +3 more sources

Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. [PDF]

J Clin Invest, 2021
Cortical spreading depression (CSD), a wave of depolarization followed by depression of cortical activity, is a pathophysiological process implicated in migraine with aura and various other brain pathologies, such as ischemic stroke and traumatic brain ...
Auffenberg E, Hedrich UB, Barbieri R, Miely D, Groschup B, Wuttke TV, Vogel N, Lührs P, Zanardi I, Bertelli S, Spielmann N, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Pusch M, Dichgans M, Lerche H, Gavazzo P, Plesnila N, Freilinger T.   +19 more
europepmc   +2 more sources

Diversity of cortical activity changes beyond depression during Spreading Depolarizations

Nature Communications, 2023
Spreading depolarizations (SDs) are classically thought to be associated with spreading depression of cortical activity. Here, we found that SDs in patients with subarachnoid hemorrhage produce variable, ranging from depression to booming, changes in ...
Azat Nasretdinov, Daria Vinokurova, Coline L. Lemale, Gulshat Burkhanova-Zakirova, Ksenia Chernova, Julia Makarova, Oscar Herreras, Jens P. Dreier, Roustem Khazipov   +8 more
doaj   +2 more sources

Efficacy profile of noninvasive vagus nerve stimulation on cortical spreading depression susceptibility and the tissue response in a rat model. [PDF]

J Headache Pain, 2022
Background Noninvasive vagus nerve stimulation (nVNS) has recently emerged as a promising therapy for migraine. We previously demonstrated that vagus nerve stimulation inhibits cortical spreading depression (CSD), the electrophysiological event ...
Liu TT, Morais A, Takizawa T, Mulder I, Simon BJ, Chen SP, Wang SJ, Ayata C, Yen JC.   +8 more
europepmc   +2 more sources

Src family kinases activity is required for transmitting purinergic P2X7 receptor signaling in cortical spreading depression and neuroinflammation. [PDF]

J Headache Pain, 2021
Background Purinergic P2X7 receptor plays an important role in migraine pathophysiology. Yet precise molecular mechanism underlying P2X7R signaling in migraine remains unclear.
Nie L, Ma D, Quinn JP, Wang M.
europepmc   +2 more sources

Nitric Oxide Formation during Cortical Spreading Depression is Critical for Rapid Subsequent Recovery of Ionic Homeostasis [PDF]

, 2002
NoCortical spreading depression (CSD) is a temporary disruption of local ionic homeostasis that propagates slowly across the cerebral cortex. Cortical spreading depression promotes lesion progression in experimental stroke, and may contribute to the ...
Tihomir P. Obrenovitch, Jutta Urenjak, Minyan Wang   +2 more
openalex   +3 more sources