Results 61 to 70 of about 10,427 (246)

Hair analysis of formoterol as a novel tool to assess long‐term inhalation medication adherence: Data from the TRICOLON trial

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this paper is to examine inhaled formoterol concentrations in hair and assess the potential of hair analysis as a tool for measuring long‐term adherence, by validation with objective data from digital inhalers. Methods Hair samples and digital inhaler data were collected from patients with COPD in 10 hospitals in the Netherlands as part ...
Liz J. A. Cuperus, A. Mireille A. Wessels, Huib A. M. Kerstjens, Daan J. Touw, Erik W. M. A. Bischoff, Job van der Palen, Arnoud Aldenkamp, Astrid van Huisstede, Folkert Brijker, Stephan Dik, Lidwien Graat‐Verboom, Martijn Goosens, Peter Th. W. van Hal, Jolanda C. Kuijvenhoven, Lisette I. Z. Kunz, Renske van der Meer, Mariette H. A. Scholma‐Bronsema, Job F. M. van Boven, Johannes C. C. M. in't Veen, the TRICOLON study group, Marjo van der Poel, Irini Piso, Marijke Amelink, Anke Rol, Jennifer de Graaf, Petra Hirmann, Fleur van Tour, Elly Jordens, Lydia Alfing, Gerda Lenderink, Truus Rietveld, Jasmijn van Campen, Jantine de Bruijn, Janice van ter Burg, Liselore Baarssmit, Walter van Litsenburg, Len Knoops, Margot Eggermont‐Schilt, Manon de Waard‐Heijligers, Ilonka Paalvast‐Schouten, Mariette Scholma, Sandra Brookman‐Mozes, Inge Paas, Lidwien Verboom, Karin van Mierlo‐Snoeijs   +44 more
wiley   +1 more source

Endogenous Na+, K+-ATPase inhibitors and CSF [Na+] contribute to migraine formation.

PLoS ONE, 2019
There is strong evidence that neuronal hyper-excitability underlies migraine, and may or may not be preceded by cortical spreading depression. However, the mechanisms for cortical spreading depression and/or migraine are not established. Previous studies
Noah B Gross, Nastaren Abad, David Lichtstein, Shiri Taron, Lorena Aparicio, Alfred N Fonteh, Xianghong Arakaki, Robert P Cowan, Samuel C Grant, Michael G Harrington   +9 more
doaj   +1 more source

Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine

Brain Sciences, 2019
Migraine is a disorder characterized by attacks of monolateral headaches, often accompanied by nausea, vomiting, and photophobia. Around 30% of patients also report aura symptoms.
Salvo Danilo Lombardo, Emanuela Mazzon, Maria Sofia Basile, Eugenio Cavalli, Placido Bramanti, Riccardo Nania, Paolo Fagone, Ferdinando Nicoletti, Maria Cristina Petralia   +8 more
doaj   +1 more source

Housing Warmth/Coolness and Quietness Correlate With Whole‐Brain Fractional Anisotropy in Healthy Adults

Brain Health, EarlyView.
ABSTRACT Introduction Residential environments have been linked to brain structure, particularly in children, older adults, and clinical populations. However, little is known about how different dimensions of the housing environment relate to brain white matter microstructure in healthy adults, or whether specific environmental factors show stronger ...
Keisuke Kokubun, Kiyotaka Nemoto, Toshiharu Ikaga, Yoshinori Yamakawa   +3 more
wiley   +1 more source

Susceptibility Weighted Imaging as a Biomarker for Cortical Spreading Depression

Clinical and Translational Neuroscience
Introduction: Cortical spreading depression (CSD) is thought to be the pathophysiologic correlate of migraine aura. In experimental animals, CSD was shown to cause an increase in oxyhemoglobin.
Adrian Scutelnic, Isabelle Dominique Stöckli, Antonia Klein, Franz Riederer, Nedelina Slavova, Christoph J. Schankin   +5 more
doaj   +1 more source

Reward Processing in Binge Eating and Harmful Drinking: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating and harmful drinking commonly co‐occur, which worsens the physical and psychological consequences associated with either behavior alone. Reward processing alterations have been demonstrated among individuals who engage in binge eating or harmful drinking alone; however, there is limited understanding of how different ...
Taylor N. Breddy, Kendall M. Schmidt, Lindsay P. Bodell   +2 more
wiley   +1 more source

Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice

Advanced Science
Cortical traveling waves coordinate communication among distributed neural ensembles to modulate brain function and dysfunction through distinct spatiotemporal propagation patterns.
Jiaming Liu, Jia‐Wen Mo, Xunda Wang, Yinuo Ma, Shile Tian, Qi Wang, Peng‐Li Kong, Ziqi An, Li Ding, Jing Ren, Cheng‐Lin Lu, Chuanjun Tong, Ed X. Wu, Qiu‐gen Hu, Xiong Cao, Yanqiu Feng   +15 more
doaj   +1 more source

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

ELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam   +3 more
wiley   +1 more source

Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5

Neuropsychiatric Disease and Treatment, 2016
Emanuela Viggiano,1,2 Vincenzo Monda,1 Antonietta Messina,1 Fiorenzo Moscatelli,3 Anna Valenzano,3 Domenico Tafuri,4 Giuseppe Cibelli,3 Bruno De Luca,1 Giovanni Messina,1,3 Marcellino Monda1 1Department of Experimental Medicine, Section of Human ...
Viggiano E, Monda V, Messina A, Moscatelli F, Valenzano A, Tafuri D, Cibelli G, De Luca B, Messina G, Monda M   +9 more
doaj  

Neuro-ophthalmology and migraine: visual aura and its neural basis

International Journal of Emergency Medicine
Background Migraine, a chronic neurological condition often accompanied by visual aura, which affects 15–33% of migraineurs, often presents as transient visual disturbances such as scintillating scotoma and teichopsia. These symptoms arise primarily from
Hajar Nasir Tukur, Olivier Uwishema, Dalal Sheikhah, Hatice Akbay   +3 more
doaj   +1 more source