Results 81 to 90 of about 1,302,249 (240)

Susceptibility Weighted Imaging as a Biomarker for Cortical Spreading Depression

Clinical and Translational Neuroscience
Introduction: Cortical spreading depression (CSD) is thought to be the pathophysiologic correlate of migraine aura. In experimental animals, CSD was shown to cause an increase in oxyhemoglobin.
Adrian Scutelnic, Isabelle Dominique Stöckli, Antonia Klein, Franz Riederer, Nedelina Slavova, Christoph J. Schankin   +5 more
doaj   +1 more source

Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa, Leandro Rodrigo Ribeiro, Jéssica Lorena Bariviera, Mauro Schneider Oliveira   +3 more
wiley   +1 more source

Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5

Neuropsychiatric Disease and Treatment, 2016
Emanuela Viggiano,1,2 Vincenzo Monda,1 Antonietta Messina,1 Fiorenzo Moscatelli,3 Anna Valenzano,3 Domenico Tafuri,4 Giuseppe Cibelli,3 Bruno De Luca,1 Giovanni Messina,1,3 Marcellino Monda1 1Department of Experimental Medicine, Section of Human ...
Viggiano E, Monda V, Messina A, Moscatelli F, Valenzano A, Tafuri D, Cibelli G, De Luca B, Messina G, Monda M   +9 more
doaj  

Neuro-ophthalmology and migraine: visual aura and its neural basis

International Journal of Emergency Medicine
Background Migraine, a chronic neurological condition often accompanied by visual aura, which affects 15–33% of migraineurs, often presents as transient visual disturbances such as scintillating scotoma and teichopsia. These symptoms arise primarily from
Hajar Nasir Tukur, Olivier Uwishema, Dalal Sheikhah, Hatice Akbay   +3 more
doaj   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Changes in Cortical pH and Blood Flow Accompanying Spreading Cortical Depression and Convulsion

, 1957
Local changes in cerebral cortex hydrogen ion concentration of as much as 0.5 ph units were observed to accompany the waves of cortical spreading depression or convulsion in cats and rabbits. A diphasic wave consisting of an initial alkaline followed by
Kazutoyo Inanaga, Ralph R. Sonnenschein, J. Langdon Taylor, Robert M. Walker, Robert D. Tschirgi   +4 more
core   +1 more source

An unusual titanosaur axis from the Upper Cretaceous of Brazil and its significance for sauropod anatomy and systematics

The Anatomical Record, EarlyView.
Abstract The Upper Cretaceous São José do Rio Preto Formation (Bauru Group, southeastern Brazil) has yielded a fragmentary but taxonomically diverse record of titanosaur sauropods, although elements from cervical series remain scarce. Here, we describe a nearly complete sauropod axis from the Vila Ventura Paleontological Area, representing an uncommon ...
Bruno A. Navarro, Jeffrey A. Wilson Mantilla, Jhonata H. A. Martins, Fabiano V. Iori, Leonardo S. Paschoa, Alberto B. Carvalho, Joseli M. Piranha, Hussam Zaher   +7 more
wiley   +1 more source

Elevation in body temperature may increase susceptibility to cortical spreading depression in a rat model

Neuroscience Research
One characteristic of migraine is recurrent headache attacks, which are known to be induced by changes in climatic variables such as atmospheric pressure, humidity, and outside temperature.
Eiji Kitamura, Naomi Kanazawa, Takahiro Iizuka, Kazutoshi Nishiyama   +3 more
doaj   +1 more source

Familial Hemiplegic Migraine with Prolonged Coma and Hyperthermia: ATP1A2 Gene Mutation Case Report in a Single Saudi Family.

Journal of Biochemical and Clinical Genetics, 2019
Background: Familial hemiplegic migraine (FHM) is a rare disorder presented commonly with coma, hyperthermia, and headache. FHM is usually associated with fully reversible motor weakness as a specific symptom of aura.
Waleed Altwaijri, Fuad Almalki, Ahmed Al-Rumayyan, Safiyyah Asiri   +3 more
doaj   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source