Results 101 to 110 of about 12,036 (197)

A Corticobasal Syndrome Variant of Familial Creutzfeldt-Jakob Disease with Stroke-Like Onset

Case Reports in Neurological Medicine, 2016
Creutzfeldt-Jakob disease (CJD) is an untreatable rare human prion disease characterized by rapidly progressive dementia along with various neurological features, including myoclonus and sometimes other movement disorders.
Ján Necpál, Martin Stelzer, Silvia Koščová, Michal Patarák   +3 more
doaj   +1 more source

Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]

, 2019
Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill, Gunter, Jeffrey L, Haley, Dana, Jones, David, Kantarci, Kejal, Knopman, David, Kraft, Ruth, Lapid, Maria, Lesnick, Timothy, Rademakers, Rosa, Rosen, Howie, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +22 more
core   +3 more sources

Alzheimer's disease polygenic risk in early‐ and late‐onset Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The genetic basis of sporadic early‐onset Alzheimer's disease (EOAD) remains largely unknown, prompting evaluation of late‐onset Alzheimer's disease (LOAD) polygenic risk in EOAD. METHODS A LOAD polygenic score (PGS) was calculated in the Longitudinal Early‐onset Alzheimer's Disease Study (LEADS) and Alzheimer's Disease ...
Julian V. Pentchev, Trever Jackson, Naazneen Khan, Thea J. Rosewood, Yen‐Ning Huang, Kwangsik Nho, Andrew J. Saykin, Ani Eloyan, Alexander Taurone, Maryanne Thangarajah, Meghan Riddle, Steven Salloway, Alireza Atri, Lawrence S. Honig, Erik C. B. Johnson, Raymond Scott Turner, Joseph C. Masdeu, Tatiana M. Foroud, David Clark, Dustin B. Hammers, Jeffrey L. Dage, Kala Kirby, Bernardino Ghetti, Kathy Newell, Chiadi U. Onyike, Gregory S. Day, Neill R. Graff‐Radford, Melissa E. Murray, David T. Jones, Clifford R. Jack Jr., Prashanthi Vemuri, Alexandra Touroutoglou, Ranjan Duara, Ian Grant, Sharon Sha, Thomas S. Wingo, Laurel A. Beckett, Emily Rogalski, Mario F. Mendez, Joel Kramer, Renaud La Joie, Ganna Blazhenets, Lea T. Grinberg, Robert Koeppe, David A. Wolk, Paul Aisen, Rema Raman, Arthur Toga, Walter A. Kukull, Erik Musiek, Kyle B. Womack, Maria C. Carrillo, Gil D. Rabinovici, Bradford C. Dickerson, Liana G. Apostolova, Kelly N. H. Nudelman, for the Longitudinal Early‐Onset Alzheimer's Disease Study Consortium and the Alzheimer's Disease Neuroimaging Initiative   +56 more
wiley   +1 more source

Clinical Approach to Progressive Supranuclear Palsy [PDF]

, 2016
Sixty years ago, Steele, Richardson and Olszewski designated progressive supranuclear palsy (PSP) as a new clinicopathological entity in their seminal paper. Since then, in addition to the classic Richardson's syndrome (RS), different clinical phenotypic
Ling, H
core   +2 more sources

The Language Profile of Behavioral Variant Frontotemporal Dementia [PDF]

, 2016
BACKGROUND: The language profile of behavioral variant frontotemporal dementia (bvFTD) remains to be fully defined. OBJECTIVE: We aimed to quantify the extent of language deficits in this patient group.
Buckley, AH, Crutch, SJ, Downey, LE, Hardy, CJ, Lehmann, M, Rohrer, JD, Varley, RA, Warren, JD, Warrington, EK, Zimmerer, VC   +9 more
core   +1 more source

Diagnostic Value of Bedside Eye Movement Examination in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Eloísa Bittencurt Thomaz de Assis, Paula Martínez Ruiz, Cristina Acosta Gudiel, Hüseyin Nezih Özdemir, Diego Kaski   +4 more
wiley   +1 more source

Acting without being in control: Exploring volition in Parkinson's disease with impulsive compulsive behaviours. [PDF]

, 2017
BACKGROUND: Several aspects of volitional control of action may be relevant in the pathophysiology of impulsive-compulsive behaviours (ICB) in Parkinson's disease (PD).
de Boer, L, Edwards, MJ, Haggard, P, Morgante, F, Ricciardi, L, Sorbera, C, Stenner, M-P   +6 more
core   +2 more sources

Cerebrospinal Fluid Total and Phosphorylated Tau Protein in Behavioral Variant Frontotemporal Dementia, Progressive Supranuclear Palsy, Corticobasal Syndrome and Non-Fluent Agrammatic Primary Progressive Aphasia: A Systematic Review and Meta-Analysis

Biomedicines
(1) Background: Frontotemporal lobar degeneration (FTLD) is a generic term which refers to multiple pathologies, including FTLD-tau. The most common FTLD-tau diseases are Pick’s disease (PiD), progressive supranuclear palsy (PSP) and corticobasal ...
Nikolaos Giagkou, Ioanna Kapsali, Maria-Evgenia Brinia, Vasilios C. Constantinides   +3 more
doaj   +1 more source

Utility of the new Movement Disorder Society clinical diagnostic criteria for Parkinson's disease applied retrospectively in a large cohort study of recent onset cases [PDF]

, 2017
Objective: To examine the utility of the new Movement Disorder Society (MDS) diagnostic criteria in a large cohort of Parkinson's disease (PD) patients.
,, Bajaj, Nin, Barker, Roger A., Ben-Shlomo, Yoav, Burn, David J., Foltynie, Tom, Grosset, Donald G., Grosset, Katherine A., Hardy, John, Lawton, Michael A., Malek, Naveed, Morris, Huw R., Williams, Nigel M., Wood, Nicholas   +13 more
core   +5 more sources

Rates of lobar atrophy in asymptomatic MAPT mutation carriers. [PDF]

, 2019
IntroductionThe aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule-associated protein tau (MAPT) mutation carriers.MethodsMAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill R, Jack, Clifford R, Jones, David T, Kantarci, Kejal, Knopman, David S, Kremers, Walter K, Lapid, Maria, LEFFTDS Consortium, Lesnick, Timothy G, Rademakers, Rosa, Rosen, Howie, Senjem, Matthew, Syrjanen, Jeremy, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +24 more
core   +2 more sources