Familial neurodegenerative disease with parkinsonism syndrome and amyotrophic lateral sclerosis
The concurrence of amyotrophic lateral sclerosis (ALS) with parkinsonism syndrome and dementia is described as Guam ALS, in which up to 70% of patients have a positive family history.
T. K. Davydova +5 more
doaj +1 more source
18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy. [PDF]
The ability to assess the distribution and extent of tau pathology in Alzheimer's disease and progressive supranuclear palsy in vivo would help to develop biomarkers for these tauopathies and clinical trials of disease-modifying therapies.
Aigbirhio, Franklin I +17 more
core +1 more source
Clinical utility of FDG PET in Parkinson's disease and atypical parkinsonism associated with dementia [PDF]
PURPOSE: There are no comprehensive guidelines for the use of FDG PET in the following three clinical scenarios: (1) diagnostic work-up of patients with idiopathic Parkinson's disease (PD) at risk of future cognitive decline, (2) discriminating ...
Agosta, F +13 more
core +1 more source
Reply to “Neurophysiological Testing to Diagnose Stiff‐Person Spectrum Disorder”
Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 303-304, January 2026.
João Moura +5 more
wiley +1 more source
Introduction: Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) manifest with variable clinical features. We initiated a multicenter prospective registry study—the Japanese Longitudinal Biomarker Study in PSP and CBD—in November ...
Hiroshi Takigawa +14 more
doaj +1 more source
Neologistic jargon aphasia and agraphia in primary progressive aphasia [PDF]
The terms 'jargon aphasia' and 'jargon agraphia' describe the production of incomprehensible language containing frequent phonological, semantic or neologistic errors in speech and writing, respectively.
Rohrer, JD, Rossor, MN, Warren, JD
core
Botulinum toxin for the treatment of dystonia and pain in corticobasal syndrome
Background Dystonia is a key symptom in corticobasal syndrome (CBS), and upper limb dystonia is the most common phenotype. Dystonia‐associated pain is frequently reported and can be disabling, with poor benefit from oral treatments.
Elisa Unti +6 more
doaj +1 more source
Case report: Behavioral variant FTD confounding a language variant FTD in a case of PSP-CBS
Frontotemporal dementia (FTD) occurs in two main clinical subtypes, which can transition into one another: the behavioral variant (bvFTD) and the language variant (primary progressive aphasia; PPA).
Alexandra V. Jürs +9 more
doaj +1 more source
Background/Objectives: Transferrin is a multi-task protein commonly known for binding iron; however, it is involved in multiple crucial processes, including antimicrobial activity, the growth of different cell types, differentiation, chemotaxis, the cell
Natalia Madetko-Alster +4 more
doaj +1 more source
Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years [PDF]
To date, cerebrospinal fluid analysis, particularly protein 14-3-3 testing, presents an important approach in the identification of Creutzfeldt-Jakob disease cases.
Aguzzi, Adriano +20 more
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