Results 171 to 180 of about 12,036 (197)

CORTICOBASAL SYNDROME AND CORTICOBASAL DEGENERATION

Journal of Neurology, Neurosurgery & Psychiatry, 2016
Corticobasal degeneration (CBD) typically presents with asymmetric dyspraxia, stiffness and dystonia (Corticobasal syndrome – CBS). Features of CBS occur in other diseases and there are no well validated clinical or biological markers that accurately predict its underlying pathology, making diagnosis difficult.
Ruth Lamb, Marcia Darvell, John Woodside, Jon Rohrer, Andrew Lees, Huw Morris   +5 more
openaire   +1 more source

Limb apraxia in corticobasal syndrome

Cortex, 2011
Corticobasal syndrome (CBS) is a progressive neurodegenerative disorder with asymmetric presentation and course characterized by degeneration of basal ganglia and cortical structures. Limb apraxia is a commonly observed deficit in CBS. Few studies have examined comprehensively the nature of deficits in limb apraxia.
Vessela, Stamenova, Eric A, Roy, Sandra E, Black   +2 more
openaire   +2 more sources

Imaging of corticobasal degeneration syndrome

Neuroradiology, 2007
Diagnosing corticobasal degeneration is often difficult on the basis of clinical symptoms and radiological images. We aimed to clarify the imaging findings of corticobasal degeneration syndrome (CBDS).Included in the study were 16 patients (8 men, 8 women, 46-75 years old) with clinically diagnosed CBDS.
Masamichi, Koyama, Akira, Yagishita, Yasuhiro, Nakata, Masaharu, Hayashi, Mitsuaki, Bandoh, Toshio, Mizutani   +5 more
openaire   +2 more sources

277 Disentangling corticobasal syndrome from corticobasal degeneration

Journal of Neurology, Neurosurgery & Psychiatry, 2018
Mutations in the TANK-binding kinase (TBK1) gene have been shown to cause frontotemporal dementia (FTLD) and amyotrophic lateral sclerosis (ALS). The phenotype is highly variable and has been associated with behavioural variant FTD, primary progressive aphasia and pure amyotrophic lateral sclerosis. We describe the clinical, anatomical and pathological
Lamb Ruth, Rohrer Jonathan, Lubbe Steven, Weil Rimona, Lashley Tammaryn, Holten Janice, Revesz Tamas, Lees Andrew, Morris Huw   +8 more
openaire   +1 more source

Alzheimer's disease and corticobasal degeneration presenting as corticobasal syndrome

Movement Disorders, 2009
AbstractThe aim of this article is to compare patients with Alzheimer's disease (AD) pathology and corticobasal degeneration pathology (CBD) presenting as corticobasal syndrome (CBS). Clinicopathologic series was used. Five patients with AD and 11 patients with CBD were clinically diagnosed with CBS.
William T, Hu, Gregory W, Rippon, Bradley F, Boeve, David S, Knopman, Ronald C, Petersen, Joseph E, Parisi, Keith A, Josephs   +6 more
openaire   +2 more sources

Corticobasal syndrome with tau pathology

Movement Disorders, 2001
AbstractSix cases with a clinical corticobasal syndrome (progressive asymmetric apraxia and parkinsonism unresponsive to levodopa) and tau pathology were selected from 97 brain donors with parkinsonism. Postmortem volumetric measures of regional brain atrophy (compared with age/sex‐matched controls) were correlated with clinical features and the degree
N J, Cordato, G M, Halliday, H, McCann, L, Davies, P, Williamson, M, Fulham, J G, Morris   +6 more
openaire   +2 more sources

Visual Involvement in Corticobasal Syndrome

Journal of Neuro-Ophthalmology, 2012
Corticobasal syndrome (CBS) is the clinical presentation of corticobasal degeneration (CBD), a rare neurodegenerative disorder, with features of both cerebral and basal ganglia involvement. Visual disturbance is uncommonly a predominant symptom but when present can be markedly debilitating.
Rithwick, Rajagopal, Randall, Bateman, Gregory P, Van Stavern   +2 more
openaire   +2 more sources

PET-based classification of corticobasal syndrome

Parkinsonism & Related Disorders, 2022
Corticobasal degeneration (CBD) is the most common neuropathological substrate for clinically diagnosed corticobasal syndrome (CBS), while identifying CBD pathology in living individuals has been challenging. This study aimed to examine the capability of positron emission tomography (PET) to detect CBD-type tau depositions and neuropathological ...
Yoshikazu Nakano, Hitoshi Shimada, Hitoshi Shinotoh, Shigeki Hirano, Kenji Tagai, Yasunori Sano, Yasuharu Yamamoto, Hironobu Endo, Kiwamu Matsuoka, Keisuke Takahata, Manabu Kubota, Yuhei Takado, Yasuyuki Kimura, Masanori Ichise, Maiko Ono, Naruhiko Sahara, Kazunori Kawamura, Ming-Rong Zhang, Satoshi Kuwabara, Tetsuya Suhara, Makoto Higuchi   +20 more
openaire   +2 more sources

Swallowing disturbances in the corticobasal syndrome

Parkinsonism & Related Disorders, 2015
To determine the characteristics of swallowing and speech disturbances in patients with corticobasal syndrome (CBS) compared to healthy controls, and whether a subjective swallowing questionnaire, the NIH-Speech Pathology swallowing questionnaire (NIH-SQ), can predict swallowing impairment.Twenty-four consecutive CBS patients underwent a swallowing ...
M. Grunho, B. Sonies, C.M. Frattali, I. Litvan   +3 more
openaire   +2 more sources

Progressive Supranuclear Palsy and Corticobasal Syndrome

Continuum, 2022
The differential diagnosis of parkinsonism (tremor, rigidity, bradykinesia, and gait difficulty/postural instability) is broad and includes two neurodegenerative conditions that exist on a clinicopathologic spectrum: progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS).
openaire   +2 more sources