Results 31 to 40 of about 304,978 (243)

Reintroduction of immunosuppressive medications in pediatric rheumatology patients with histoplasmosis: a case series

Pediatric Rheumatology Online Journal, 2021
Background Children with rheumatic diseases (cRD) receiving immunosuppressive medications (IM) are at a higher risk for acquiring potentially lethal pathogens, including Histoplasma capsulatum (histoplasmosis), a fungal infection that can lead to ...
Rachel A. Brown, Fatima Barbar-Smiley, Cagri Yildirim-Toruner, Monica I. Ardura, Stacy P. Ardoin, Shoghik Akoghlanian   +5 more
doaj   +1 more source

Inhaled Corticosteroids [PDF]

Pharmaceuticals, 2010
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress inflammation mainly by switching off multiple activated inflammatory genes through reversing histone acetylation via the recruitment of histone deacetylase 2 (HDAC2).
openaire   +5 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Comparing Intra-Articular Corticosteroids and Platelet-rich Plasma for Knee Osteoarthritis Pain: A Prospective Quasi-comparative Study

Indian Journal of Pain
Background and Aim: Intra-articular (I/A) corticosteroids (CS) are used for short to mid-term pain relief in knee osteoarthritis (KOA). Newer therapies such as platelet-rich plasma (PRP) are believed to induce regenerative changes and decrease pain. Ours
Khuboo Rana, Suruchi Ambasta, Shivani Rastogi, Suraj Kumar, Shamrendra Narayan, Anurag Agarwal   +5 more
doaj   +1 more source

Acute Pathophysiological Effects of Intratracheal Instillation of Budesonide and Exogenous Surfactant in a Neonatal Surfactant-depleted Piglet Model

Pediatrics and Neonatology, 2010
Chronic lung disease continues to be a major complication in premature infants with severe respiratory distress syndrome (RDS). This is despite having advanced ventilatory care, prenatal corticosteroids, and postnatal surfactant therapies.
Chia-Feng Yang, Mei-Jy Jeng, Wen-Jue Soong, Yu-Sheng Lee, Pen-Chen Tsao, Ren-Bin Tang   +5 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Successful management of chronic eosinophilic pneumonia triggered by immune checkpoint inhibitor: a case report and literature review

Frontiers in Immunology
Immune checkpoint inhibitors (ICIs) enhance antitumor immunity by blocking inhibitory immune signals, but can lead to immune-related adverse events (irAEs). Therefore, effective management of irAEs is crucial during ICI therapy.
Yasuhito Suzuki, Junpei Saito, Satoshi Kubota, Masakazu Ikeda, Mami Rikimaru, Ryuki Yamada, Takahiro Kumanaka, Ryutaro Tanaka, Kentaro Kazama, Koshi Saito, Rina Harigane, Riko Sato, Hikaru Tomita, Natsumi Watanabe, Takashi Umeda, Ryuichi Togawa, Yuki Sato, Takefumi Nikaido, Xintao Wang, Kenya Kanazawa, Yoshinori Tanino, Shigeyuki Murono, Yoko Shibata   +22 more
doaj   +1 more source

An Early Intensive Intervention for Inducing Inactive Asthma in Adults —A One-Year Follow-Up Observation Study—

Allergology International, 2011
Background: Treatment strategy that reduces dependence on long-term medication for chronic asthma is preferable. The purpose of the study is to investigate the efficacy of an early intensive intervention for inducing inactive asthma in adults and ...
Koichiro Kudo, Hiroko Arioka, Yuichiro Takeda, Takuro Shimbo, Satoko Handa, Akihiko Kawana, Mitsuhiro Kamimura, Yasuhiro Yamauchi, Hiroyuki Nagase, Nobuyuki Kobayashi, Toshie Manabe, Junzaburo Kabe   +11 more
doaj   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source