Results 121 to 130 of about 372,480 (259)
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li +19 more
wiley +1 more source
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie +7 more
wiley +1 more source
Similarities Between Corticosteroids [PDF]
Corticosteroids are a class of potent drugs with important physiological effects on the body. Regular use is linked with common and serious side effects. This paper uses studies to analyze the similarities between various corticosteroids.
Einhorn, M.
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Editorial: Corticosteroids and endothelial dysfunction ||FREE PAPER||
Reza TabrizchiDivision of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St John’s, NL, CanadaAssessment of endothelial-mediated relaxation in situ is rapidly becoming the standard gauge of individual ...
Reza Tabrizchi
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Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng +8 more
wiley +1 more source
Corticosteroids in the treatment of acute exacerbations of chronic obstructive pulmonary disease
J Andrew Woods,1 James S Wheeler,1 Christopher K Finch,2 Nathan A Pinner3 1School of Pharmacy, Wingate University, Wingate, NC, USA; 2Department of Pharmacy, Methodist University Hospital, Memphis, TN, USA; 3Harrison School of Pharmacy, Auburn University,
Finch CK +3 more
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Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li +9 more
wiley +1 more source
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
Oreoluwa Olaloko,1 Raihan Mohammed,1 Utkarsh Ojha2 1Faculty of Medicine, University of Cambridge, Cambridge, UK; 2Faculty of Medicine, Imperial College, London, UK Abstract: Approximately 15 million babies worldwide are born premature, and complications ...
Mohammed R, Olaloko O, Ojha U
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