Results 61 to 70 of about 522,558 (297)

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Safety for the Rhinologist in the Age of COVID-19: Mask Use, Nasal Corticosteroids, Saline Irrigation, and Endoscopic Procedures – Literature Review

International Archives of Otorhinolaryngology, 2022
Introduction Coronavirus disease 2019 (COVID-19) has claimed millions of lives. Adequate protection of the professionals involved in patient care is essential in the battle against this disease.
Eduardo Macoto Kosugi, Jonatas Figueiredo Villa, Henrique Faria Ramos, Gabriela Ricci Luz-Matsumoto, Thiago Luis Infanger Serrano, Carlos Augusto Correia de Campos, Carolina Cincurá Barreto, Clara Mônica Lima, Marco Aurélio Fornazieri, Otavio Piltcher, Marcus Miranda Lessa, Fabrizio Ricci Romano   +11 more
doaj   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Diagnostic Challenge in a Case of Cryptogenic Organising Pneumonia [PDF]

Journal of Clinical and Diagnostic Research
Cryptogenic Organising Pneumonia (COP) is a rare Interstitial Lung Disease (ILD) characterised by a distinctive histological pattern without a known cause.
Shailesh Bhanudas Meshram, Brahmansh Singh, Rishi Govind Orakkan, Shrividya Sethuratnam   +3 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Corticosteroids for treating sepsis in children and adults.

Cochrane Database of Systematic Reviews, 2019
BACKGROUND Sepsis occurs when an infection is complicated by organ failure. Sepsis may be complicated by impaired corticosteroid metabolism. Thus, providing corticosteroids may benefit patients.
D. Annane, É. Bellissant, P. Bollaert, J. Briegel, D. Keh, Y. Kupfer, R. Pirracchio, B. Rochwerg   +7 more
semanticscholar   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids

Journal of Experimental Medicine, 2019
Corticosteroids inhibit antitumor immune responses of immune checkpoint blockade in a dose- and timing-dependent manner. Memory CD8+ T cells with low TCR affinity are selectively suppressed by corticosteroids, necessitating careful and thoughtful ...
Akihiro Tokunaga, D. Sugiyama, Y. Maeda, A. B. Warner, K. Panageas, S. Ito, Y. Togashi, Chika Sakai, J. Wolchok, H. Nishikawa   +9 more
semanticscholar   +1 more source

Trends in Dermato‐polymyositis Mortality, 1999‐2022: A Nationwide Population‐based Study, United States

Arthritis Care &Research, Accepted Article.
Objective We evaluated trends in dermato‐polymyositis (DPM) mortality relative to all‐cause mortality in the United States, 1999‐2022. Methods We used the Center for Disease Control and Prevention's databases (Multiple Causes of Death for 1999‐2020 and Provisional Mortality Statistics for 2021 and 2022) to obtain death counts for DPM and non‐DPM (all ...
Elizabeth Matz, Ram R. Singh
wiley   +1 more source

Exclusive enteral nutrition versus corticosteroids for treatment of pediatric Crohn’s disease: a meta-analysis

World Journal of Pediatrics, 2019
BackgroundMany studies have examined the effects of exclusive enteral nutrition (EEN) in children with Crohn’s disease (CD), but corticosteroids are considered a superior therapy and are frequently used in China.
Yu Yu, Kang Chen, Jie Chen
semanticscholar   +1 more source