Results 71 to 80 of about 484,106 (362)
Journal of Pain Research, 2018 Yaofei Jiang,1–4,* Ruoxi Chen,2,* Suming Xu,2,* Jiaxi Li,2,* Fanqi Yu,2 Lingdong Kong,2 Yuhan Sun,2 Yuan Ye,2 Yimin Li,2 Mengqi Yu,2 Jiaming Wu1 1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Jiaxing University, Jiaxing ...
Jiang Y +10 more
doaj
Reduced bone mineral density in men after heart transplantation
Brazilian Journal of Medical and Biological Research, 1999 Heart transplantation is associated with rapid bone loss and an increased prevalence and incidence of fractures. The aim of the present study was to compare the bone mineral density (BMD) of 30 heart transplant (HT) recipients to that of 31 chronic heart
J.R. Anijar +4 more
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Dexamethasone implant – An update
TNOA Journal of Ophthalmic Science and Research, 2020 Uveitic entities may be infectious or noninfectious in etiology. Corticosteroids remain the first-line treatment for noninfectious posterior uveitis.
Richa Pyare, Jyotirmay Biswas
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Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Advanced Science, EarlyView.Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef +12 more
wiley +1 more source
Advanced Science, EarlyView.Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li +11 more
wiley +1 more source
Case Reports in Gastroenterology, 2020 Cronkhite-Canada syndrome (CCS) is a rare disease characterized by diffuse gastrointestinal polyposis with chronic diarrhea and ectodermal change, but its etiology is unknown.
Kazumoto Murata +5 more
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Treatment Intensification in Patients With Kawasaki Disease and Coronary Aneurysm at Diagnosis. [PDF]
, 2019 BackgroundCoronary artery aneurysms (CAA) are a serious complication of Kawasaki disease. Treatment with intravenous immunoglobulin (IVIg) within 10 days of fever onset reduces the risk of CAA from 25% to <5%.
Baker, Annette L +11 more
core
Systemic corticosteroids for acute otitis media in children [PDF]
, 2018 Background: Acute otitis media (AOM) is a common acute infection in children. Pain is its most prominent and distressing symptom. Antibiotics are commonly prescribed for AOM, although they have only a modest effect in reducing pain at two to three days.
Beller, Elaine M +6 more
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Advanced Science, EarlyView.Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang +6 more
wiley +1 more source