Results 71 to 80 of about 138,058 (298)

Targeting G‐Rich lncRNA and its Structural Polymorphism with Selective G‐Quadruplex Ligands: An NMR Study

Chemistry – A European Journal, EarlyView.
The REG1CP‐derived RNA oligonucleotide SL15P adopts a parallel G‐quadruplex (rGQ) structure. In this study, we investigate the effect of several well‐characterized ligands, originally developed for DNA GQs, on the RNA counterpart, with the aim of evaluating their binding ability and specific binding modes.
Giuseppe Satta, Jasna Brčić, Janez Plavec   +2 more
wiley   +1 more source

Experimental chronic noise is related to elevated fecal corticosteroid metabolites in lekking male greater Sage-Grouse (Centrocercus urophasianus). [PDF]

, 2012
There is increasing evidence that individuals in many species avoid areas exposed to chronic anthropogenic noise, but the impact of noise on those who remain in these habitats is unclear.
Blickley, Jessica L, Krakauer, Alan H, Patricelli, Gail L, Phillips, Jennifer L, Sells, Sarah N, Taff, Conor C, Wingfield, John C, Word, Karen R   +7 more
core   +8 more sources

Assessment of testicular corticosterone biosynthesis in adult male rats.

PLoS ONE, 2015
Corticosterone is synthesized in the adrenal glands and is circulated throughout the body to perform regulatory functions in various tissues. The testis is known to synthesize and secrete testosterone and other androgens.
Naoyuki Maeda, Sachi Tahata, Takeshi Yagi, Emi Tanaka, Kanae Masu, Michiko Sato, Satoko Haeno, Takenori Onaga, Hiroshi Yokota   +8 more
doaj   +1 more source

Triiodothyronine suppresses humoral immunity but not T-cell-mediated immune response in incubating female eiders (Somateria mollissima)

, 2007
Immunity is believed to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eiders (Somateria mollissima) is
Ahima, Apanius, Bourgeon, Bourgeon, Bourgeon, Criscuolo, Criscuolo, Deerenberg, Demas, Eraud, Erikstad, Faggioni, Fowles, Gabarrou, Gabrielsen, Gustafsson, Hanssen, Hanssen, Hanssen, Harvey, Korschgen, Lord, Lõhmus, Lõhmus, Martinez-Padilla, Martínez, Matarese, Matarese, McNabb, Merino, Moreno, Norris, Parham, Roitt, Råberg, Saino, Sechman, Sheldon, Smits, Sophie Bourgeon, Stearns, Thierry Raclot, Tomás, Verhulst, Williams, Williamson   +45 more
core   +1 more source

The Effect of High Dose Total Body Irradiation on ACTH, Corticosterone, and Catecholamines in the Rat [PDF]

, 2011
Total body irradiation (TBI) or partial body irradiation is a distinct risk of accidental, wartime, or terrorist events. Total body irradiation is also used as conditioning therapy before hematopoietic stem cell transplantation.
Bruder, Eric D., Cohen, Eric P., Cullinan, William E, Raff, Hershel, Ziegler, Dana R.   +4 more
core   +2 more sources

DSOK‐0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity‐Based Anorexia Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a metabolic‐psychiatric disorder characterized by severe weight loss, hypercortisolemia, and hypothalamic–pituitary–adrenal (HPA) axis activation. In this study, we investigated the effect of inhibiting cortisol regeneration via the enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) on the ...
Hiroki Kawai, Nanami Wada, Shinji Sakamoto, Kenji Miyazaki, Taro Kato, Yoshihiro Horiuchi, Hiroshi Kirii, Hoang Duy Nguyen, Kenji Hinotsu, Yoshio Ohya, Takahiro Asada, Akiyoshi Yokode, Yuko Okahisa, Haruko Miyazaki, Toshitaka Oohashi, Manabu Takaki   +15 more
wiley   +1 more source

Chronic treatment with glucocorticoids does not affect egg quality but increases cortisol deposition into egg albumen and elicits changes to the heterophil to lymphocyte ratio in a sex-dependent manner

Frontiers in Physiology, 2023
During chronic stress, there is an initial increase in glucocorticoid (GC) levels, but they then return to low, albeit not baseline, levels. Recent studies have renewed interest in cortisol in that it may also have important roles in the stress response.
E. M. Oluwagbenga, V. Tetel, S. Tonissen, D. M. Karcher, G. S. Fraley   +4 more
doaj   +1 more source

Interpreting Neuroendocrine Hormones, Corticosterone, and Blood Glucose to Assess the Wellbeing of Anesthetized Rats during Euthanasia [PDF]

, 2018
Current recommendations for assessing animal wellbeing during euthanasia suggest that measuring neuroendocrine hormones-such as ACTH, noradrenaline, and adrenaline-is preferable to measuring corticosterone and blood glucose because of the sensitivity of ...
Hickman, Debra L.
core   +1 more source

Powerful yet challenging: mechanistic niche models for predicting invasive species potential distribution under climate change

Ecography, EarlyView.
Risk assessments of invasive species present one of the most challenging applications of species distribution models (SDMs) due to the fundamental issues of distributional disequilibrium, niche changes, and truncation. Invasive species often occupy only a fraction of their potential environmental and geographic ranges, as their spatiotemporal dynamics ...
Erola Fenollosa, Sean E. H. Pang, Natalie J. Briscoe, Antoine Guisan, Roberto Salguero-Gómez   +4 more
wiley   +1 more source

Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways.

PLoS ONE, 2018
Extensive studies suggested epigallocatechin-3-gallate (EGCG) has significant neuroprotection against multiple central neural injuries, but the underlying mechanisms still remain poorly elucidated.
Xiaoling Zhao, Renjia Li, Hui Jin, Haimin Jin, Yonghui Wang, Wanqi Zhang, Haichao Wang, Weiqiang Chen   +7 more
doaj   +1 more source