Results 61 to 70 of about 10,599 (209)

Effects of Apical Dendrite Integrity on Action Potential Properties in Layer 6 Corticothalamic Pyramidal Neurons: Evidence for Hemispheric Differences

open access: yesBiology
Hemispheric asymmetries in the cortical structure and function are well documented, but whether this asymmetry is reflected in the electrophysiological properties of the same neuron type remains unclear, particularly given the many factors that influence
Ahmed A. Aldohbeyb
doaj   +1 more source

Diversity of Layer 5 Projection Neurons in the Mouse Motor Cortex

open access: yesFrontiers in Cellular Neuroscience, 2013
In the primary motor cortex (M1), layer 5 projection neurons signal directly to distant motor structures to drive movement. Despite their pivotal position and acknowledged diversity these neurons are traditionally separated into broad commissural and ...
Manfred J Oswald   +4 more
doaj   +1 more source

Functional representation of vision within the mind: A visual consciousness model based in 3D default space [PDF]

open access: yes, 2015
The human eyes and brain, which have finite boundaries, create a ‘‘virtual’’ space within our central nervous system that interprets and perceives a space that appears boundless and infinite.
Barnes, Vernon A.   +2 more
core  

The Gli3 Hypomorphic Mutation Pdn Causes Selective Impairment in the Growth, Patterning, and Axon Guidance Capability of the Lateral Ganglionic Eminence [PDF]

open access: yes, 2010
Previous studies have defined a requirement for Sonic hedgehog (Shh) signaling in patterning the ventral telencephalon, a major source of the neuronal diversity found in the mature telencephalon.
Campagnoni, Anthony T.   +5 more
core   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

NaV1.1 haploinsufficiency impairs glutamatergic and GABAergic neuron function in the thalamus

open access: yesNeurobiology of Disease, 2022
Thalamocortical network dysfunction contributes to seizures and sleep deficits in Dravet syndrome (DS), an infantile epileptic encephalopathy, but the underlying molecular and cellular mechanisms remain elusive. DS is primarily caused by mutations in the
Carleigh Studtmann   +4 more
doaj   +1 more source

Thalamic neuromodulation and its implications for executive networks [PDF]

open access: yes, 2014
The thalamus is a key structure that controls the routing of information in the brain. Understanding modulation at the thalamic level is critical to understanding the flow of information to brain regions involved in cognitive functions, such as the ...
Abramson   +240 more
core   +2 more sources

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Selective manipulation of excitatory and inhibitory neurons in top-down and bottom-up visual pathways using ultrasound stimulation

open access: yesBrain Stimulation
Introduction: Techniques for precise manipulation of neurons in specific neural pathways are crucial for excitatory/inhibitory (E/I) balance and investigation of complex brain circuits.
Yehhyun Jo   +8 more
doaj   +1 more source

Feedforward and feedback pathways of nociceptive and tactile processing in human somatosensory system: A study of dynamic causal modeling of fMRI data

open access: yesNeuroImage, 2021
Nociceptive and tactile information is processed in the somatosensory system via reciprocal (i.e., feedforward and feedback) projections between the thalamus, the primary (S1) and secondary (S2) somatosensory cortices.
Yingchao Song   +8 more
doaj   +1 more source

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