Results 81 to 90 of about 10,599 (209)
Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]
, 2011 GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Crunelli, Vincenzo +2 more
core
Suppression of V1 feedback produces a shift in the topographic representation of receptive fields of LGN cells by unmasking latent retinal drives [PDF]
, 2017 [Abstract] In awake monkeys, we used repetitive transcranial magnetic stimulation (rTMS) to focally inactivate visual cortex while measuring the responsiveness of parvocellular lateral geniculate nucleus (LGN) neurons. Effects were noted in 64/75 neurons,
Aguila, Jordi +2 more
core +2 more sources
The fear circuit of the mouse forebrain: connections between the mediodorsal thalamus, frontal cortices and basolateral amygdala [PDF]
, 2014 A large forebrain circuit, including the thalamus, amygdala and frontal cortical regions, is responsible for the establishment and extinction of fear-related memories.
Acsády, László +3 more
core +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, Volume 13, Issue 13, 3 March 2026.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus
eLife, 2016 Spontaneous retinal waves are critical for the development of receptive fields in visual thalamus (LGN) and cortex (VC). Despite a detailed understanding of the circuit specializations in retina that generate waves, whether central circuit ...
Yasunobu Murata, Matthew T Colonnese
doaj +1 more source
, 2015 Despite the attention attracted by "connectomics", one can lose sight of the very real questions concerning "What are connections?" In the neuroimaging community, "structural" connectivity is ground truth and underlying constraint on "functional" or ...
Rockland, K. S.
core +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
CTNN: Corticothalamic-inspired neural network
CoRR, 2019 Sensory predictions by the brain in all modalities take place as a result of bottom-up and top-down connections both in the neocortex and between the neocortex and the thalamus. The bottom-up connections in the cortex are responsible for learning, pattern recognition, and object classification, and have been widely modelled using artificial neural ...
Leendert A. Remmelzwaal +2 more
openaire +2 more sources
Looking back: corticothalamic feedback and early visual processing [PDF]
, 2006 [Abstract] Although once regarded as a simple sensory relay on the way to the cortex, it is increasingly apparent that the thalamus has a role in the ongoing moment-by-moment processing of sensory input and in cognition.
Cudeiro, Javier, Sillito, Adam M.
core +2 more sources
Implication of the thalamus in sleep alterations observed in Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is frequently accompanied by sleep disturbances. Alterations of sleep, in both quality and quantity, contribute to the progression of AD neuropathology. The thalamus, through its diverse nuclei, plays a central role in sleep regulation and sleep‐dependent memory ...
Carla Burnet‐Merlin +2 more
wiley +1 more source