Results 101 to 110 of about 29,028 (227)

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Carbonyl stress markers are associated with binge‐eating/purging behavior of anorexia nervosa: A pilot study

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
This study investigated Advanced Glycation End Products (AGEs), reflecting carbonyl stress from glycation and oxidation reactions, as potential biomarkers for identifying binge‐eating/purging behaviors in anorexia nervosa (AN). Finding revealed higher fingertip AGE levels in the binge‐eating/purging subtype (ANBP) compared to the restricting subtype ...
Kana Morimoto, Masanori Isobe, Tomomi Noda, Keima Tose, Momo Sunada, Koichi Tabata, Momoka Taniguchi, Makoto Arai, Toshiya Murai   +8 more
wiley   +1 more source

The Role of Corticotropin-Releasing Factor (CRF) and CRF-Related Peptides in the Social Behavior of Rodents. [PDF]

Biomedicines, 2023
Bagosi Z, Megyesi K, Ayman J, Rudersdorf H, Ayaz MK, Csabafi K.   +5 more
europepmc   +1 more source

The neuropsychological impact of early childhood trauma on cognitive development: A narrative review of mechanisms, outcomes, and interventions

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Research indicates that early traumatic experiences can profoundly affect a child's ability to manage emotions, develop social skills, and adapt effectively. Still, the impact of trauma on children goes beyond just emotional and behavioral dimensions.
Kalliopi Megari, Kremena Dinkova Genova
wiley   +1 more source

Corticotropin-releasing factor-like diuretic hormone acts as a gonad-inhibiting hormone in adult female, Rhodnius prolixus. [PDF]

Front Endocrinol (Lausanne), 2023
Al-Dailami AN, Orchard I, Lange AB.
europepmc   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

Equine Veterinary Education, Volume 38, Issue 9, Page e622-e630, September 2026.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken, H. Tyra, M. Vetter, K. Kiger, S. Rao, L. Bass   +5 more
wiley   +1 more source

Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV, James M. Salvatore, Matthew J. Sticco, Keaven Caro, J. Wesley Maddox, Angie Huang, Brenna C. McAllister, Christopher B. O'Connell, Siu‐Pok Yee, Amy Lee, Susanne Ressl, David C. Martinelli, Alexander C. Jackson   +12 more
wiley   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, Volume 11, Issue 4, Page 1263-1275, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Gut microbiota‐targeted interventions for depression in adolescents and young adults: Mechanisms, evidence strength and clinical strategies—A narrative review

General Psychiatry, Volume 39, Issue 4, August 2026.
ABSTRACT Depression in adolescents and young adults is common, associated with substantial functional impairment and characterised by limited treatment efficacy. The microbiota–gut–brain (MGB) axis has emerged as a potential therapeutic target for depression.
Hanchen Hou, Yinan Li, Wanting Tang, Yiwen Gao, Yuanyuan Tian, Fei Chen, Lige Zhang, Jushuang Zhang, Xiaoxia Xu, Yao Li, Yi Li, Qingshan Wang, Lingli Liu, Teng Teng, Hao Wu, Xinyu Zhou   +15 more
wiley   +1 more source