Results 1 to 10 of about 515,964 (279)

Corticotropin-Releasing Hormone: Biology and Therapeutic Opportunities [PDF]

Biology, 2022
In 1981, Wylie Vale, Joachim Spiess, Catherine Rivier, and Jean Rivier reported on the characterization of a 41-amino-acid peptide from ovine hypothalamic extracts with high potency and intrinsic activity stimulating the secretion of adrenocorticotropic ...
Alessandra Caruso, Alessandra Gaetano, Sergio Scaccianoce   +2 more
doaj   +4 more sources

Crucial role of corticotropin-releasing hormone, corticotropin-releasing hormone -binding protein, mir-200c, and mir-181a in preterm delivery: A case-control study [PDF]

International Journal of Reproductive BioMedicine, 2023
Background Preterm birth before 37 th wk of gestation is called premature birth. Corticotropin-releasing hormone (CRH) and CRH-binding protein (BP) act on various maternal and fetal tissues during pregnancy, such as the myometrium, which regulates the ...
Ehsan Mohiti Ardakani, Mahta Mazaheri2comma, Ph.D., Mohsen Forouzanfar, Mahdieh Mojibian, Mojtaba Jafarinia   +5 more
doaj   +2 more sources

Corticotropin-Releasing Hormone in Melanoma and Nonmelanoma Skin Cancer [PDF]

Journal of Skin Cancer
Conclusion: CRH does not necessarily correlate with the degree of malignancy, as semimalignant cancers such as BCC show higher levels of CRH expression than SCCs. In melanoma, CRH expression in metastases may be an important prognostic factor for overall
Marcel Mueller, Susanne Melchers, Iris Mueller, Jochen Utikal, Julia Krug, Astrid Schmieder   +5 more
doaj   +2 more sources

Corticotropin releasing hormone is present in the feline placenta and maternal serum [PDF]

Frontiers in Endocrinology, 2023
BackgroundIn women, placental corticotropin releasing hormone (CRH) can be detected in maternal blood throughout pregnancy and is important in the regulation of the timing of parturition. However, its role in other mammalian species is unclear.
Madison Watt, Pardis Mohammadzadeh, Emma Pinsinski, Fiona K. Hollinshead, Gerrit J. Bouma   +4 more
doaj   +2 more sources

Neuroimmune connections between corticotropin-releasing hormone and mast cells: novel strategies for the treatment of neurodegenerative diseases

Neural Regeneration Research, 2021
Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis, which plays a major role in the body’s immune response to stress.
Piplu Bhuiyan, Yi-Wei Wang, Huan-Huan Sha, Hong-Quan Dong, Yan-Ning Qian   +4 more
doaj   +1 more source

Brain corticotropin releasing hormone and stress reactivity

Интегративная физиология, 2021
The hypothalamic-pituitary-adrenocortical axis is one of the main components of stress adaptation. Corticotropin-releasing hormone (CRH) coming from the nucleus paraventricularis hypothalami (PVN) is the canonical central regulator of the axis.
Krisztina Bánrévi, Tiago Chaves, Pedro Correia, Csilla Lea Fazekas, Adrienn Szabó, Bibiána Török, Dóra Zelena   +6 more
doaj   +1 more source

Placental hormone profiles as predictors of preterm birth in twin pregnancy: A prospective cohort study. [PDF]

PLoS ONE, 2017
The objective of the study was to analyse placental hormone profiles in twin pregnancies to determine if they could be used to predict preterm birth.Progesterone, estradiol, estriol and corticotropin-releasing hormone were measured using competitive ...
Hui Lim, Sioned Powell, Helen C Mcnamara, A Forbes Howie, Ann Doust, Maria E Bowman, Roger Smith, Jane E Norman, Sarah J Stock   +8 more
doaj   +1 more source

Characterizing the postnatal hypothalamic–pituitary–adrenal axis response of in utero heat stressed pigs at 10 and 15 weeks of age

Scientific Reports, 2021
In utero heat stress alters postnatal physiological and behavioral stress responses in pigs. However, the mechanisms underlying these alterations have not been determined.
Jacob M. Maskal, Luiz F. Brito, Alan W. Duttlinger, Kouassi R. Kpodo, Betty R. McConn, Christopher J. Byrd, Brian T. Richert, Jeremy N. Marchant, Donald C. Lay, Shelbi D. Perry, Matthew C. Lucy, Tim J. Safranski, Jay S. Johnson   +12 more
doaj   +1 more source

Antiapoptotic effects of velvet antler polypeptides on damaged neurons through the hypothalamic-pituitary-adrenal axis [PDF]

Journal of Integrative Neuroscience, 2020
We investigated the effects of velvet antler polypeptide on cognitive impairment and the underlying mechanisms. Hydrogen peroxide-induced cell injury was used to establish an in vitro model of SH-SY5Y cells.
Qing Yang, Jia-Nan Lin, Xin Sui, Hui Li, Mo Kan, Ji-Feng Wang, Jing Li, Zhuang Zhang, Xiao-Ran Liu, Si-Tong Ming, Xiao-Bo Qu, Na Li
doaj   +1 more source

The Effect of Craniosacral Therapy on Blood Levels of Stress Hormones in Male Firefighter Cadets: A Randomized Clinical Trial

Behavioral Sciences, 2023
(1) Background: Fire department cadets preparing to become firefighters and paramedics experience high levels of stress when participating in incidents like traffic accidents and fires. Stress adversely affects health, and coping with it proves difficult.
Małgorzata Wójcik, Bruno Bordoni, Idzi Siatkowski, Ewa Żekanowska   +3 more
doaj   +1 more source