Corticotropin-Releasing Hormone: Biology and Therapeutic Opportunities [PDF]
Biology, 2022 In 1981, Wylie Vale, Joachim Spiess, Catherine Rivier, and Jean Rivier reported on the characterization of a 41-amino-acid peptide from ovine hypothalamic extracts with high potency and intrinsic activity stimulating the secretion of adrenocorticotropic ...
Alessandra Caruso +2 more
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Crucial role of corticotropin-releasing hormone, corticotropin-releasing hormone -binding protein, mir-200c, and mir-181a in preterm delivery: A case-control study [PDF]
International Journal of Reproductive BioMedicine, 2023 Background Preterm birth before 37 th wk of gestation is called premature birth. Corticotropin-releasing hormone (CRH) and CRH-binding protein (BP) act on various maternal and fetal tissues during pregnancy, such as the myometrium, which regulates the ...
Ehsan Mohiti Ardakani +5 more
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Corticotropin-Releasing Hormone in Melanoma and Nonmelanoma Skin Cancer [PDF]
Journal of Skin CancerConclusion: CRH does not necessarily correlate with the degree of malignancy, as semimalignant cancers such as BCC show higher levels of CRH expression than SCCs. In melanoma, CRH expression in metastases may be an important prognostic factor for overall
Marcel Mueller +5 more
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Corticotropin releasing hormone is present in the feline placenta and maternal serum [PDF]
Frontiers in Endocrinology, 2023 BackgroundIn women, placental corticotropin releasing hormone (CRH) can be detected in maternal blood throughout pregnancy and is important in the regulation of the timing of parturition. However, its role in other mammalian species is unclear.
Madison Watt +4 more
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Corticotropin releasing hormone-expressing inputs to the thalamic paraventricular nucleus: pathways from mother to memory? [PDF]
Neurobiology of StressThalamic paraventricular nucleus (PVT) neurons expressing the corticotropin releasing hormone receptor 1 (CRHR1) are preferentially activated during early life stress.
Jorge M. Mendoza +5 more
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Research Progress of Central and Peripheral Corticotropin-Releasing Hormone in Irritable Bowel Syndrome with Comorbid Dysthymic Disorders [PDF]
Gut and LiverIrritable bowel syndrome (IBS) is considered a stress disorder characterized by psychological and gastrointestinal dysfunction. IBS patients not only suffer from intestinal symptoms such as abdominal pain, diarrhea, or constipation but also, experience ...
Yi Feng Liang +4 more
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Neural Regeneration Research, 2021 Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis, which plays a major role in the body’s immune response to stress.
Piplu Bhuiyan +4 more
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Brain corticotropin releasing hormone and stress reactivity
Интегративная физиология, 2021 The hypothalamic-pituitary-adrenocortical axis is one of the main components of stress adaptation. Corticotropin-releasing hormone (CRH) coming from the nucleus paraventricularis hypothalami (PVN) is the canonical central regulator of the axis.
Krisztina Bánrévi +6 more
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Placental hormone profiles as predictors of preterm birth in twin pregnancy: A prospective cohort study. [PDF]
PLoS ONE, 2017 The objective of the study was to analyse placental hormone profiles in twin pregnancies to determine if they could be used to predict preterm birth.Progesterone, estradiol, estriol and corticotropin-releasing hormone were measured using competitive ...
Hui Lim +8 more
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Antiapoptotic effects of velvet antler polypeptides on damaged neurons through the hypothalamic-pituitary-adrenal axis [PDF]
Journal of Integrative Neuroscience, 2020 We investigated the effects of velvet antler polypeptide on cognitive impairment and the underlying mechanisms. Hydrogen peroxide-induced cell injury was used to establish an in vitro model of SH-SY5Y cells.
Qing Yang, Jia-Nan Lin, Xin Sui, Hui Li, Mo Kan, Ji-Feng Wang, Jing Li, Zhuang Zhang, Xiao-Ran Liu, Si-Tong Ming, Xiao-Bo Qu, Na Li
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