Results 21 to 30 of about 32,652 (160)

Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter. [PDF]

PLoS ONE, 2013
The ability to identify predictors of aversive events allows organisms to appropriately respond to these events, and failure to acquire these fear contingencies can lead to maladaptive contextual anxiety.
Ivo Heitland, Lucianne Groenink, Elisabeth Y Bijlsma, Ronald S Oosting, Johanna M P Baas   +4 more
doaj   +1 more source

Idiopathic and isolated adrenocorticotropic hormone deficiency presenting as continuous epigastric discomfort without symptoms of hypoglycemia: a case report

Journal of Medical Case Reports, 2019
Background Isolated adrenocorticotropic hormone deficiency is one kind of hypopituitarism and is triggered by various diseases including autoimmune disorder and/or autoimmune hypophysitis. Adrenocorticotropic hormone deficiency brings out various serious
Seizo Okauchi, Fuminori Tatsumi, Yuki Kan, Megumi Horiya, Akiko Mizoguchi, Yoshiro Fushimi, Junpei Sanada, Momoyo Nishioka, Masashi Shimoda, Kenji Kohara, Shuhei Nakanishi, Kohei Kaku, Tomoatsu Mune, Hideaki Kaneto   +13 more
doaj   +1 more source

Transcriptional regulation of corticotropin-releasing hormone gene in stress response

IBRO Reports, 2018
As a central player of the hypothalamic-pituitary-adrenal (HPA) axis, the corticotropin -releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) determine the state of HPA axis and play a key role in stress response.
Jiang-Ning Zhou, Hui Fang
doaj   +1 more source

Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast

Frontiers in Cell and Developmental Biology, 2021
We previously showed that maternal leukemia inhibitory factor (LIF) induces placental production of adrenocorticotropic hormone (ACTH), which stimulates fetal nucleated red blood cells to further secrete LIF and promote neurogenesis in rodent brains ...
He Wang, He Wang, Hiromi Sakata-Haga, Hiroko Masuta, Mitsuhiro Tomosugi, Tsuyoshi Tsukada, Hiroki Shimada, Daisuke Sakai, Hiroki Shoji, Toshihisa Hatta   +9 more
doaj   +1 more source

Endocrinology and the brain: corticotropin-releasing hormone signaling

Endocrine Connections, 2017
Corticotropin-releasing hormone (CRH) is a key player of basal and stress-activated responses in the hypothalamic–pituitary–adrenal axis (HPA) and in extrahypothalamic circuits, where it functions as a neuromodulator to orchestrate humoral and behavioral
Carolina Inda, Natalia G Armando, Paula A dos Santos Claro, Susana Silberstein   +3 more
doaj   +1 more source

Cell Type-Specific Expression of Corticotropin-Releasing Hormone-Binding Protein in GABAergic Interneurons in the Prefrontal Cortex

Frontiers in Neuroanatomy, 2017
Corticotropin-releasing hormone-binding protein (CRH-BP) is a secreted glycoprotein that binds CRH with very high affinity to modulate CRH receptor activity.
Kyle D. Ketchesin, Kyle D. Ketchesin, Nicholas S. Huang, Audrey F. Seasholtz, Audrey F. Seasholtz, Audrey F. Seasholtz   +5 more
doaj   +1 more source

Moderate white light exposure enhanced spatial memory retrieval by activating a central amygdala-involved circuit in mice

Communications Biology, 2023
Light exposure can profoundly affect neurological functions and behaviors. Here, we show that short-term exposure to moderate (400 lux) white light during Y-maze test promoted spatial memory retrieval and induced only mild anxiety in mice.
MengJuan Shang, MeiLun Shen, RuoTong Xu, JingYu Du, JiMeng Zhang, Ding OuYang, JunZe Du, JunFeng Hu, ZhiChuan Sun, BingXia Wang, Qian Han, Yang Hu, YiHong Liu, Yun Guan, Jing Li, GuoZhen Guo, JunLing Xing   +16 more
doaj   +1 more source

Pathophysiology of Infantile Spasms

Pediatric Neurology Briefs, 1993
An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of ...
J Gordon Millichap
doaj   +1 more source

Corticotropin releasing hormone promotes inflammatory bowel disease via inducing intestinal macrophage autophagy

Cell Death Discovery, 2021
Psychosocial stress is a vital factor contributing to the pathogenesis and progression of inflammatory bowel disease (IBD). The contribution of intestinal macrophage autophagy to the onset and development of IBD has been widely studied.
Sheng-Bing Zhao, Jia-Yi Wu, Zi-Xuan He, Yi-Hang Song, Xin Chang, Tian Xia, Xue Fang, Zhao-Shen Li, Can Xu, Shu-Ling Wang, Yu Bai   +10 more
doaj   +1 more source

HYPOTHALAMIC NEUROHORMONES AND IMMUNE RESPONSES

Frontiers in Integrative Neuroscience, 2013
The aim of this review is to provide a comprehensive examination of the current literature describing the neural-immune interactions, with emphasis on the most recent findings of the effects of neurohormones on immune system.
J. Luis eQuintanar, Irene eGuzmán-Soto
doaj   +1 more source