Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear.
Joon S. Kim +2 more
doaj +1 more source
Evaluation of Alcohol Preference and Drinking in msP Rats Bearing a Crhr1 Promoter Polymorphism
Alcoholism is a pervasive societal problem, yet available pharmacotherapies fail to treat most sufferers. The type 1 corticotropin-releasing factor (CRF1) receptor has received much attention for its putative role in the progression to alcohol dependence,
Marian L. Logrip +8 more
doaj +1 more source
Roles of Reproductive Corticotropin‐Releasing Hormone
Abstract: Corticotropin‐releasing hormone (CRH), the principal regulator of the hypothalamic‐pituitary‐adrenal axis, as well as its receptors, have been identified in most female reproductive tissues, including the uterus, placenta, and ovary. Endometrial CRH may participate in decidualization, implantation, and early maternal tolerance; placental CRH
Kalantaridou, S.N. +3 more
openaire +4 more sources
cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells
Corticotropin-releasing hormone receptor 1 (CRHR1) activates the atypical soluble adenylyl cyclase (sAC) in addition to transmembrane adenylyl cyclases (tmACs).
Carolina Inda +6 more
doaj +1 more source
Relevance of inferior petrosal sinus sampling in the diagnosis of Cushing’s syndrome: a case report
Non-specific signs and symptoms of Cushing’s syndrome (CS) can pose a diagnostic challenge.
García Clara Jiménez +4 more
doaj +1 more source
tHE ROLE OF corticotropin-RELEASING HORMONE IN INITIATION OF LABOR
Purpose: To determine the content of corticotropin-releasing hormone, substance P, prostaglandin F2a, neurokinins A and B, interleukins 6 and 8, relaxin and cortisol in the blood serum and amniotic fluid and to evaluate the influence of these markers on ...
T. G. Arutyunyan +2 more
doaj +1 more source
Functional characterization of two corticotropin-releasing hormone receptors in Larimichthys crocea
In the neuroendocrine system, corticotropin-releasing hormone (CRH) plays an important role in the hypothalamic–pituitary–adrenal/interrenal (HPA/HPI) axis. It exerts its effects by activating CRHRs, which belong to the class B G protein-coupled receptor
Xue Liu +7 more
doaj +1 more source
Electrophysiological Effects of Ghrelin in the Hypothalamic Paraventricular Nucleus Neurons
The paraventricular nucleus (PVN) is involved in the control of sympathetic tone and the secretion of hormones, both functions known to be influenced by ghrelin, suggesting direct effect of ghrelin in this nucleus.
Raoni C. dos-Santos +5 more
doaj +1 more source
The hypothalamic-pituitary-adrenal (HPA) axis controls the secretion of corticotropin-releasing hormone (CRH), corticotropin (adrenocorticotropic hormone, ACTH), and cortisol.
Leo Sher
doaj +1 more source
Corticotropin releasing hormone and the skin [PDF]
Cotricotropin-releasing hormone (CRH) and related peptides are produced in skin that is dependent on species and anatomical location. Local peptide production is regulated by ultraviolet radiation (UVR), glucocorticoids and phase of the hair cycle. The skin also expresses the corresponding receptors (CRH-R1 and CRH-R2), with CRH-R1 being the major ...
Andrzej, Slominski +6 more
openaire +2 more sources

