Results 41 to 50 of about 32,652 (160)

Corticotropin-releasing hormone receptor 1 gene variants in irritable bowel syndrome. [PDF]

PLoS ONE, 2012
BackgroundCorticotropin-releasing hormone (CRH) acts mainly via the CRH receptor 1 (CRH-R1) and plays a crucial role in the stress-induced pathophysiology of irritable bowel syndrome (IBS).
Naoko Sato, Naoki Suzuki, Ayaka Sasaki, Emiko Aizawa, Takeshi Obayashi, Motoyori Kanazawa, Tomoko Mizuno, Michiko Kano, Masashi Aoki, Shin Fukudo   +9 more
doaj   +1 more source

Corticotropin-releasing hormone physiology [PDF]

European Journal of Endocrinology, 2006
Corticotropin-releasing hormone (CRH), also known as corticotropin-releasing factor, is a highly conserved peptide hormone comprising 41 amino acid residues. Its name derives from its role in the anterior pituitary, where it mediates the release of corticotropin (ACTH) leading to the release of adrenocortical steroids.
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Clinical Perspectives of Urocortin and Related Agents for the Treatment of Cardiovascular Disease

International Journal of Endocrinology, 2012
The effects of corticotropin-releasing hormone, also known as corticotropin-releasing factor (CRF), on the cardiovascular system have been intensively researched since its discovery. Moreover, the actions of urocortin (Ucn) I on the cardiovascular system
Keiichi Ikeda, Kouki Fujioka, Yoshinobu Manome, Katsuyoshi Tojo   +3 more
doaj   +1 more source

Promoter Methylation Pattern Controls Corticotropin Releasing Hormone Gene Activity in Human Trophoblasts.

PLoS ONE, 2017
Placental CRH production increases with advancing pregnancy in women and its course predicts gestational length. We hypothesized that CRH gene expression in the placenta is epigenetically controlled setting gestational trajectories characteristic of ...
Xin Pan, Maria Bowman, Rodney J Scott, John Fitter, Roger Smith, Tamas Zakar   +5 more
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The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress

Molecular Cancer, 2010
Introduction Stress has been shown to be a tumor promoting factor. Both clinical and laboratory studies have shown that chronic stress is associated with tumor growth in several types of cancer.
Stathopoulos Efstathios N, Ripoll Jorge, Rassouli Olga, Dermitzaki Erini, Androulidaki Ariadne, Mol Berber, Venihaki Maria, Arranz Alicia, Gomariz Rosa P, Margioris Andrew N, Tsatsanis Christos   +10 more
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Modulation of Sleep Homeostasis by Corticotropin Releasing Hormone in REM Sleep-Deprived Rats

International Journal of Endocrinology, 2010
Studies have shown that sleep recovery following different protocols of forced waking varies according to the level of stress inherent to each method.
Ricardo Borges Machado, Sergio Tufik, Deborah Suchecki   +2 more
doaj   +1 more source

Crossover of the hypothalamic pituitary-adrenal/interrenal (HPA), -thyroid (HPT), and -gonadal (HPG) axes in testicular development

Frontiers in Endocrinology, 2014
Besides the well-known function of thyroid hormones (THs) for regulating metabolism, it has recently been discovered that THs are also involved in testicular development in mammalian and non-mammalian species.
Diana C. Castañeda Cortés, Valerie S. Langlois, Juan I. Fernandino   +2 more
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Case Report: ACTH- and CRH-secreting pheochromocytoma as a very rare cause of ectopic Cushing syndrome

Frontiers in Endocrinology
Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) represents a rare clinical entity characterized by severe hypercortisolemia. Pheochromocytoma, a neuroendocrine neoplasm originating from chromaffin cells within the adrenal medulla, is itself an ...
Barbara Bromińska, Nadia Sawicka-Gutaj, Ewelina Szczepanek-Parulska, Małgorzata Lange-Ratajczak, Tomasz Wierzbicki, Małgorzata Janicka-Jedyńska, Rafał Czepczyński, Marek Ruchała   +7 more
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Chronic Stress Reduces Nectin-1 mRNA Levels and Disrupts Dendritic Spine Plasticity in the Adult Mouse Perirhinal Cortex

Frontiers in Cellular Neuroscience, 2018
In adulthood, chronic exposure to stressful experiences disrupts synaptic plasticity and cognitive function. Previous studies have shown that perirhinal cortex-dependent object recognition memory is impaired by chronic stress. However, the stress effects
Qian Gong, Yun-Ai Su, Yun-Ai Su, Chen Wu, Tian-Mei Si, Tian-Mei Si, Jan M. Deussing, Mathias V. Schmidt, Xiao-Dong Wang   +8 more
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Human corticotropin-releasing hormone during pregnancy

Gynecological Endocrinology, 1989
Elevated irCRH levels up to 14 ng/ml were measured in 176 females in the last trimester. The highest maternal CRH levels were found in those females in whom the period from the onset of labour to full dilatation of the cervix and the time span of delivery were shortest.
G K, Stalla, H, Bost, J, Stalla, T, Kaliebe, H G, Dörr, D, Pfeiffer, K, von Werder, O A, Müller   +7 more
openaire   +2 more sources