Results 71 to 80 of about 56,895 (205)

CRF1 receptor activation increases the response of neurons in the basolateral nucleus of the amygdala to afferent stimulation

Frontiers in Behavioral Neuroscience, 2008
The basolateral nucleus (BLA) of the amygdala contributes to the consolidation of memories for emotional or stressful events. The nucleus contains a high density of CRF1 receptors that are activated by corticotropin-releasing factor (CRF).
doaj   +1 more source

Protective effects of urocortin 2 against caerulein-induced acute pancreatitis. [PDF]

, 2019
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats. Male
Bhargava, Aditi, Chheda, Chintan, Hasdemir, Burcu, Pandol, Stephen J, Rivier, Jean, Tan, Tanya, Yuan, Jingzhen   +6 more
core   +1 more source

Suppression of piriform cortex activity in rat by corticotropin-releasing factor 1 and serotonin 2A/C receptors

Frontiers in Cellular Neuroscience, 2015
The piriform cortex (PC) is richly innervated by Corticotropin-releasing factor (CRF) and Serotonin (5-HT) containing axons arising from central amygdala and Raphe nucleus. CRFR1 and 5-HT2A/2CRs have been shown to interact in manner where CRFR activation
Chakravarthi eNarla, Henry A Dunn, Stephen SG Ferguson, Michael O Poulter   +3 more
doaj   +1 more source

Anatomical Organization of Urocortin 3-Synthesizing Neurons and Immunoreactive Terminals in the Central Nervous System of Non-Human Primates [Sapajus spp.]

Frontiers in Neuroanatomy, 2017
Urocortin 3 (UCN3) is a neuropeptide member of the corticotropin-releasing factor (CRF) peptide family that acts as a selective endogenous ligand for the CRF, subtype 2 (CRF2) receptor.
Daniella S. Battagello, Daniella S. Battagello, Giovanne B. Diniz, Paulo L. Candido, Paulo L. Candido, Joelcimar M. da Silva, Amanda R. de Oliveira, Kelly R. Torres da Silva, Kelly R. Torres da Silva, Claudimara F. P. Lotfi, José A. de Oliveira, Luciane V. Sita, Cláudio A. Casatti, Cláudio A. Casatti, David A. Lovejoy, Jackson C. Bittencourt, Jackson C. Bittencourt   +16 more
doaj   +1 more source

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]

, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Koch, Alexander, Hamann, Lutz, Schott, Matthias, Boehm, Olaf, Grotemeyer, Dirk, Kurt, Muhammed, Schwenke, Carsten, Schumann, Ralf R., Bornstein, Stefan R., Zacharowski, Kai   +9 more
core   +1 more source

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Allolio, B., Reincke, Martin, Winkelmann, W., Würth, G.   +3 more
core  

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Maternal Cerebrospinal Fluid Glutamate in Response to Variable Foraging Demand: Relationship to Cerebrospinal Fluid Serotonin Metabolites in Grown Offspring

Chronic Stress, 2018
Background Maternal response to allostatic overload during infant rearing may alter neurobiological measures in grown offspring, potentially increasing susceptibility to mood and anxiety disorders. We examined maternal cerebrospinal fluid (CSF) glutamate
Jeremy D. Coplan, Nishant K. Gupta, Sarah K. Flynn, Wade J. Reiner, David Gaita, Sasha L. Fulton, Anna V. Rozenboym, Jean E. Tang, Thomas B. Cooper, J. John Mann   +9 more
doaj   +1 more source

Environmental manipulations generate bidirectional shifts in both behavior and gene regulation in a crossbred mouse model of extremes in trait anxiety [PDF]

, 2014
Although gene-environment interactions are known to significantly influence psychopathology related disease states, only few animal models cover both the genetic background and environmental manipulations.
Chekmareva, N., Czibere, L., Diepold, R., Landgraf, R., Naik, R., Sotnikov, S.   +5 more
core   +2 more sources

Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer’s disease-like tau hyperphosphorylation

Environmental Health and Preventive Medicine, 2017
Background Chronic noise exposure has been associated with tau hyperphosphorylation and Alzheimer’s disease (AD)-like pathological changes, but the underlying mechanism is unknown. In this study, we explored the effects of long-term noise exposure on the
Zhihui Gai, Donghong Su, Yawen Wang, Wenlong Li, Bo Cui, Kang Li, Xiaojun She, Rui Wang   +7 more
doaj   +1 more source