Results 111 to 120 of about 246,209 (305)

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Stress-induced salivary cortisol secretion during hypobaric hypoxia challenge and in vivo urinary thromboxane production in healthy male subjects.

, 2011
Few studies have assessed the effects of stress on in vivo platelet activation. In the present study, hypobaric hypoxia induced by rapid decompression during high-altitude simulated flight in a hypobaric chamber was used to evaluate the effects of ...
SIMEONI, SIMONA, PATACCHIOLI, Francesca Romana, L. Mucci, G. Davi, R. Biselli, S. Lattanzio, D'AMELIO, Raffaele, Bianca Cristina Rocca, Rocca, Bianca   +8 more
core   +1 more source

The effect of a trapping procedure on the stress response of wild rainbow trout [PDF]

, 2002
Fish traps are a common research and management tool in which fish are subjected to procedures that elicit a stress response in other contexts. The effects of trapping on the stress response of sexually mature, wild rainbow trout Oncorhynchus mykiss were
Clements, Shaun P., Hicks, Brendan J.
core   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Exploring the Relationship between Childhood Interpersonal Violence, Cortisol Stress Response, and Stress Eating [PDF]

, 2013
Histories of childhood interpersonal violence have been linked to overweight and obesity in adulthood. Despite the fact that victimization experiences are likely to co-occur within individuals, few studies have examined poly-victimization in the context ...
Midei, Aimee J
core  

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Au(I) Complex With an Abnormal Carbene Ligand Shows Anti‐Kasha Dual Photoluminescence Emission

Angewandte Chemie, EarlyView.
Incorporation of an abnormal N‐heterocyclic carbene into a heteroleptic linear Au(I) complex induces anti‐Kasha dual emission responsive to biologically relevant phenyl sulfate. ABSTRACT We report the first photoactive linear Au(I) complex with an abnormal N‐heterocyclic carbene (aNHC) ligand, Au(aIm)(Cz).
Natesan Mannangatti Rajendran, Seung Beom Cheon, Jungbin Shin, Ye Bin Jang, Taeyoon Kim, Youngmin You   +5 more
wiley   +2 more sources

The Role of Awakening Cortisol and Psychological Distress in Diurnal Variations in Affect: A Day Reconstruction Study [PDF]

People often feel unhappy in the morning but better later in the day, and this pattern may be amplified in the distressed. Past work suggests that one function of cortisol is to energize people in the mornings. In a study of 174 students we tested to see
Peter P. Doran, Malcolm MacLachlan, Michael Daly, Liam Delaney   +3 more
core  

Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women [PDF]

, 2001
In several studies lactation has been shown to be associated with a hypothalamic-pituitary-adrenal axis hyporesponsiveness to physical and psychological stressors. As it is not known whether the marked blunting of endocrine stress reactivity in women can
Heinrichs, M., Neumann, Inga, Hellhammer, Dirk H, Wagner, Sabine, Ehlert, Ulrike; https://orcid.org/, Ehlert, U., Neumann, I., Ehlert, Ulrike, Hellhammer, D. H., Kirschbaum, Clemens, M. Heinrichs, Heinrichs, Markus, Meinlschmidt, G., Wagner, S., Kirschbaum, C., Meinlschmidt, Gunther, Hellhammer, Dirk H.   +16 more
core   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source