Results 21 to 30 of about 150,986 (239)

Contribution of Non-canonical Cortisol Actions in the Early Modulation of Glucose Metabolism of Gilthead Sea Bream (Sparus aurata)

Frontiers in Endocrinology, 2019
Teleost fish are exposed to diverse stressors in farming and wildlife conditions during their lifespan. Cortisol is the main glucocorticoid hormone involved in the regulation of their metabolic acclimation under physiological stressful conditions.
Jorge E. Aedo, Jorge E. Aedo, Ignacio Ruiz-Jarabo, Gonzalo Martínez-Rodríguez, Sebastián Boltaña, Alfredo Molina, Alfredo Molina, Juan A. Valdés, Juan A. Valdés, Juan M. Mancera   +9 more
doaj   +1 more source

Analysis of cortisol levels in breast milk and blood serum in women with symptoms of postpartum depression

Medycyna Ogólna i Nauki o Zdrowiu, 2022
Introduction and objective Scientific studies report that the risk of symptoms of postpartum depression (PPD) can significantly reduce breastfeeding time. It has not yet been shown whether there is a difference in cortisol levels in breast milk and serum
Agnieszka Dombrowska-Pali, Agnieszka Chrustek, Grażyna Gebuza, Marzena Kaźmierczak   +3 more
doaj   +1 more source

Prognostic Value of Cortisol Index of Endobiogeny in Acute Myocardial Infarction Patients

Medicina, 2021
Background and Objectives: Serum cortisol has been extensively studied for its role during acute myocardial infarction (AMI). Reports have been inconsistent, with high and low serum cortisol associated with various clinical outcomes. Several publications
Rima Braukyliene, Kamyar Hedayat, Laura Zajanckauskiene, Martynas Jurenas, Ramunas Unikas, Ali Aldujeli, Osvaldas Petrokas, Vytautas Zabiela, Rasa Steponaviciute, Astra Vitkauskiene, Brigita Hedayat, Sandrita Simonyte, Vaiva Lesauskaite, Jean Claude Lapraz, Diana Zaliaduonyte   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Diurnal patterns of salivary cytokines differentially correlate with greater fluctuations in cortisol and diet composition: A pilot study

Journal of Agriculture and Food Research
Chronic stress and elevated cortisol are associated with adverse metabolic profiles and lifestyle patterns, systemic low-grade inflammation, and increased chronic disease risk; however, it is less clear how the degree of cortisol fluctuations impacts ...
Catherine J. Andersen, Brian G. Walker, Thomas J. Karanian, Allison Sloan, Courtney Campbell, Lydia Dupree, Rachael Woodruff   +6 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Comparison of salivary and serum cortisol levels in mechanically ventilated patients and non-critically ill patients [PDF]

Acute and Critical Care, 2020
Background Although the measuring free cortisol is ideal for assessment of hypothalamic-pituitary-adrenal function, it is not routinely measured. Salivary cortisol correlates well with the biologically active free cortisol. Therefore, this study measured
Jung Hee Kim, Yoon Ji Kim, Sang-Min Lee, Jinwoo Lee   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Cortisol and adrenocorticotropic hormone concentrations in horses with systemic inflammatory response syndrome

Journal of Veterinary Internal Medicine, 2019
Background Plasma adrenocorticotropic hormone (ACTH) and serum cortisol concentrations increase with illness‐associated stress. Dynamics of plasma ACTH and serum cortisol concentrations in adult horses with systemic illness are undocumented.
Allison J. Stewart, Eileen Hackett, Francois‐Rene Bertin, Taylor J. Towns   +3 more
doaj   +1 more source