Results 31 to 40 of about 39,594 (255)

Advances in Synthetic Biology Techniques and Industrial Applications of Corynebacterium glutamicum

open access: yesFermentation, 2023
Corynebacterium glutamicum is a Gram-positive bacterium (non-spore-forming) that has been wildly used for amino acid production. Due to its stable protein secretion, low extracellular hydrolase activity, and non-toxicity, the application field of C ...
Yujue Wang   +7 more
doaj   +1 more source

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

open access: yesThe Cell Surface, 2018
Arabinogalactan (AG) is an essential structural macromolecule present in the cell wall of Mycobacterium tuberculosis, serving to connect peptidoglycan with the outer mycolic acid layer.
Luke J. Alderwick   +5 more
doaj   +1 more source

Novel Chromosome Organization Pattern in Actinomycetales—Overlapping Replication Cycles Combined with Diploidy

open access: yesmBio, 2017
Bacteria regulate chromosome replication and segregation tightly with cell division to ensure faithful segregation of DNA to daughter generations. The underlying mechanisms have been addressed in several model species.
Kati Böhm   +5 more
doaj   +1 more source

Characterization of OxyR as a negative transcriptional regulator that represses catalase production in Corynebacterium diphtheriae. [PDF]

open access: yesPLoS ONE, 2012
Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Δcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H(2)O(2). In C.
Ju-Sim Kim, Randall K Holmes
doaj   +1 more source

Production of l-glutamate family amino acids in Corynebacterium glutamicum: Physiological mechanism, genetic modulation, and prospects

open access: yesSynthetic and Systems Biotechnology, 2021
l-glutamate family amino acids (GFAAs), consisting of l-glutamate, l-arginine, l-citrulline, l-ornithine, l-proline, l-hydroxyproline, γ-aminobutyric acid, and 5-aminolevulinic acid, are widely applied in the food, pharmaceutical, cosmetic, and animal ...
Qi Sheng   +5 more
doaj   +1 more source

Identifying the Growth Modulon of Corynebacterium glutamicum [PDF]

open access: yesFrontiers in Microbiology, 2019
The growth rate (μ) of industrially relevant microbes, such as Corynebacterium glutamicum, is a fundamental property that indicates its production capacity. Therefore, understanding the mechanism underlying the growth rate is imperative for improving productivity and performance through metabolic engineering.
Thorsten Haas   +8 more
openaire   +5 more sources

Construction and application of a CRISPR/Cas9-assisted genomic editing system for Corynebacterium glutamicum

open access: yesAMB Express, 2021
Corynebacterium glutamicum is widely used as microbial cell factory for various bioproducts, but its genomic editing efficiency needs to be improved. In this study, a highly efficient CRISPR/Cas9-assisted genomic editing system for C.
Chengzhen Yao   +2 more
doaj   +1 more source

Metabolic Engineering in Corynebacterium glutamicum

open access: yes, 2020
Corynebacterium glutamicum strain development has adopted each metabolic engineering tool immediately upon its conception and has contributed to developing these tools further. In the last more than five decades, C. glutamicum strains have been selected and screened after undirected mutagenesis.
Wendisch, Volker F.   +3 more
openaire   +2 more sources

CRISPR/Cas9-mediated ssDNA Recombineering in Corynebacterium glutamicum

open access: yesBio-Protocol, 2018
Corynebacterium glutamicum is a versatile workhorse for industrial bioproduction of many kinds of chemicals and fuels, notably amino acids. Development of advanced genetic engineering tools is urgently demanded for systems metabolic engineering of C ...
Jiao Liu, Yu Wang, Ping Zheng, Jibin Sun
doaj   +1 more source

Metabolic Engineering for Valorization of Agri- and Aqua-Culture Sidestreams for Production of Nitrogenous Compounds by Corynebacterium glutamicum

open access: yesFrontiers in Microbiology, 2022
Corynebacterium glutamicum is used for the million-ton-scale production of amino acids. Valorization of sidestreams from agri- and aqua-culture has focused on the production of biofuels and carboxylic acids.
Volker F. Wendisch   +2 more
doaj   +1 more source

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