Results 41 to 50 of about 50,392 (258)
AMB Express, 2021 Corynebacterium glutamicum is widely used as microbial cell factory for various bioproducts, but its genomic editing efficiency needs to be improved. In this study, a highly efficient CRISPR/Cas9-assisted genomic editing system for C.
Chengzhen Yao +2 more
doaj +1 more source
Communications Biology, 2020 Synthetic methylotrophy has recently been intensively studied to achieve methanol-based biomanufacturing of fuels and chemicals. However, attempts to engineer platform microorganisms to utilize methanol mainly focus on enzyme and pathway engineering ...
Yu Wang +13 more
semanticscholar +1 more source
Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum
Metabolic Engineering, 2021 Bacteriocins are antimicrobial peptides produced by bacteria to inhibit competitors in their natural environments. Some of these peptides have emerged as commercial food preservatives and, due to the rapid increase in antibiotic resistant bacteria, are ...
Oliver Goldbeck +18 more
semanticscholar +1 more source
Metabolic Engineering in Corynebacterium glutamicum
, 2020 Corynebacterium glutamicum strain development has adopted each metabolic engineering tool immediately upon its conception and has contributed to developing these tools further. In the last more than five decades, C. glutamicum strains have been selected and screened after undirected mutagenesis.
Wendisch, Volker F. +3 more
openaire +2 more sources
The DtxR Regulon ofCorynebacterium glutamicum [PDF]
Journal of Bacteriology, 2006 ABSTRACTPrevious studies withCorynebacterium diphtheriaeandMycobacteriumspecies revealed that the transcriptional regulator DtxR and its ortholog IdeR play a central role in the control of iron metabolism. In the present work, we used genome-based approaches to determine the DtxR regulon ofCorynebacterium glutamicum, a nonpathogenic relative ofC ...
Wennerhold, J., Bott, M.
openaire +3 more sources
CRISPR/Cas9-mediated ssDNA Recombineering in Corynebacterium glutamicum
Bio-Protocol, 2018 Corynebacterium glutamicum is a versatile workhorse for industrial bioproduction of many kinds of chemicals and fuels, notably amino acids. Development of advanced genetic engineering tools is urgently demanded for systems metabolic engineering of C ...
Jiao Liu, Yu Wang, Ping Zheng, Jibin Sun
doaj +1 more source
Frontiers in Microbiology, 2022 Corynebacterium glutamicum is used for the million-ton-scale production of amino acids. Valorization of sidestreams from agri- and aqua-culture has focused on the production of biofuels and carboxylic acids.
Volker F. Wendisch +2 more
doaj +1 more source
Development and experimental verification of a genome-scale metabolic model for [PDF]
, 2009 Background In silico genome-scale metabolic models enable the analysis of the characteristics of metabolic systems of organisms. In this study, we reconstructed a genome-scale metabolic model of Corynebacterium glutamicum on the basis of genome sequence ...
Hirasawa Takashi +5 more
core +2 more sources
Cloning vector system for Corynebacterium glutamicum [PDF]
Journal of Bacteriology, 1985 A protoplast transformation system has been developed for Corynebacterium glutamicum by using a C. glutamicum-Bacillus subtilis chimeric vector. The chimera was constructed by joining a 3.0-kilobase cryptic C. glutamicum plasmid and the B. subtilis plasmid pBD10. The neomycin resistance gene on the chimera, pHY416, was expressed in C.
M, Yoshihama +7 more
openaire +2 more sources
AMB Express, 2017 Ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA) is a lignin-derived phenolic compound abundant in plant biomass. The utilization of FA and its conversion to valuable compounds is desired.
Naoko Okai +7 more
doaj +1 more source