Bioresources and Bioprocessing, 2022 l-Ornithine, an important non-essential amino acid, has considerable medicinal value in the treatment of complex liver diseases. Microbial fermentation strategies using robust engineered strains have remarkable potential for producing l-ornithine.
Libin Nie +6 more
doaj +1 more source
Advances in Synthetic Biology Techniques and Industrial Applications of Corynebacterium glutamicum
Fermentation, 2023 Corynebacterium glutamicum is a Gram-positive bacterium (non-spore-forming) that has been wildly used for amino acid production. Due to its stable protein secretion, low extracellular hydrolase activity, and non-toxicity, the application field of C ...
Yujue Wang +7 more
doaj +1 more source
Metabolic engineering of Corynebacterium glutamicum for producing branched chain amino acids
Microbial Cell Factories, 2021 Background Branched chain amino acids (BCAAs) are widely applied in the food, pharmaceutical, and animal feed industries. Traditional chemical synthetic and enzymatic BCAAs production in vitro has been hampered by expensive raw materials, harsh reaction ...
Shengzhu Yu +3 more
semanticscholar +1 more source
The Cell Surface, 2018 Arabinogalactan (AG) is an essential structural macromolecule present in the cell wall of Mycobacterium tuberculosis, serving to connect peptidoglycan with the outer mycolic acid layer.
Luke J. Alderwick +5 more
doaj +1 more source
Ion torrent-based transcriptional assessment of a Corynebacterium pseudotuberculosis equi strain reveals denaturing high-performance liquid chromatography a promising rRNA depletion method [PDF]
, 2013 Corynebacterium pseudotuberculosis equi is a Gram-positive pathogenic bacterium which affects a variety of hosts. Besides the great economic losses it causes to horse-breeders, this organism is also known to be an important infectious agent to cattle and
Azarani +44 more
core +1 more source
mBio, 2017 Bacteria regulate chromosome replication and segregation tightly with cell division to ensure faithful segregation of DNA to daughter generations. The underlying mechanisms have been addressed in several model species.
Kati Böhm +5 more
doaj +1 more source
Transport kinetics of ectoine, an osmolyte produced by Brevibacterium epidermis [PDF]
, 2006 Brevibacterium epidermis DSM 20659 is a halotolerant Gram-positive bacterium which can synthesize the osmolyte, ectoine, but prefers to take it up from its environment. The present study revealed that B.
De Mey, Marjan +4 more
core +1 more source
In silico identification of essential proteins in Corynebacterium pseudotuberculosis based on protein-protein interaction networks [PDF]
, 2016 Background Corynebacterium pseudotuberculosis (Cp) is a gram-positive bacterium that is classified into equi and ovis serovars. The serovar ovis is the etiological agent of caseous lymphadenitis, a chronic infection affecting sheep and goats, causing ...
Azevedo, Vasco +9 more
core +5 more sources
Characterization of OxyR as a negative transcriptional regulator that represses catalase production in Corynebacterium diphtheriae. [PDF]
PLoS ONE, 2012 Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Δcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H(2)O(2). In C.
Ju-Sim Kim, Randall K Holmes
doaj +1 more source
Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine [PDF]
, 2012 Background: Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism.
Barduhn, Tobias +5 more
core +1 more source