Results 11 to 20 of about 10,021 (182)
Optimizing recombineering in Corynebacterium glutamicum [PDF]
Biotechnology and Bioengineering, 2021 AbstractOwing to the increasing demand for amino acids and valuable commodities that can be produced by Corynebacterium glutamicum, there is a pressing need for new rapid genome engineering tools that improve the speed and efficiency of genomic insertions, deletions, and mutations.
Cheng Li +3 more
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Physiological Response of Corynebacterium glutamicum to Indole [PDF]
Microorganisms, 2020 The aromatic heterocyclic compound indole is widely spread in nature. Due to its floral odor indole finds application in dairy, flavor, and fragrance products. Indole is an inter- and intracellular signaling molecule influencing cell division, sporulation, or virulence in some bacteria that synthesize it from tryptophan by tryptophanase ...
Walter, Tatjana +8 more
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Evolutionary engineering of Corynebacterium glutamicum [PDF]
Biotechnology Journal, 2019 A unique feature of biotechnology is that we can harness the power of evolution to improve process performance. Rational engineering of microbial strains has led to the establishment of a variety of successful bioprocesses, but it is hampered by the overwhelming complexity of biological systems.
Stella, Roberto G. +3 more
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The DtxR Regulon ofCorynebacterium glutamicum [PDF]
Journal of Bacteriology, 2006 ABSTRACTPrevious studies withCorynebacterium diphtheriaeandMycobacteriumspecies revealed that the transcriptional regulator DtxR and its ortholog IdeR play a central role in the control of iron metabolism. In the present work, we used genome-based approaches to determine the DtxR regulon ofCorynebacterium glutamicum, a nonpathogenic relative ofC ...
Wennerhold, J., Bott, M.
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Cloning vector system for Corynebacterium glutamicum [PDF]
Journal of Bacteriology, 1985 A protoplast transformation system has been developed for Corynebacterium glutamicum by using a C. glutamicum-Bacillus subtilis chimeric vector. The chimera was constructed by joining a 3.0-kilobase cryptic C. glutamicum plasmid and the B. subtilis plasmid pBD10. The neomycin resistance gene on the chimera, pHY416, was expressed in C.
M, Yoshihama +7 more
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Metabolic Engineering in Corynebacterium glutamicum
, 2020 Corynebacterium glutamicum strain development has adopted each metabolic engineering tool immediately upon its conception and has contributed to developing these tools further. In the last more than five decades, C. glutamicum strains have been selected and screened after undirected mutagenesis.
Wendisch, Volker F. +3 more
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Bioresources and Bioprocessing, 2022 l-Ornithine, an important non-essential amino acid, has considerable medicinal value in the treatment of complex liver diseases. Microbial fermentation strategies using robust engineered strains have remarkable potential for producing l-ornithine.
Libin Nie +6 more
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Advances in Synthetic Biology Techniques and Industrial Applications of Corynebacterium glutamicum
Fermentation, 2023 Corynebacterium glutamicum is a Gram-positive bacterium (non-spore-forming) that has been wildly used for amino acid production. Due to its stable protein secretion, low extracellular hydrolase activity, and non-toxicity, the application field of C ...
Yujue Wang +7 more
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mBio, 2017 Bacteria regulate chromosome replication and segregation tightly with cell division to ensure faithful segregation of DNA to daughter generations. The underlying mechanisms have been addressed in several model species.
Kati Böhm +5 more
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Characterization of OxyR as a negative transcriptional regulator that represses catalase production in Corynebacterium diphtheriae. [PDF]
PLoS ONE, 2012 Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Δcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H(2)O(2). In C.
Ju-Sim Kim, Randall K Holmes
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