Results 71 to 80 of about 64,617 (246)

Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a Porphyridium Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract

Marine Drugs
Red microalga Porphyridium cruentum produces a sulfated exopolysaccharide (EPS), which enables its survival in challenging intertidal and spray zones. Extracellular polysaccharide hyaluronic acid (HA) plays important roles in skin hydration, elasticity ...
Fabien Havas, Shlomo Krispin, Moshe Cohen, Joan Attia-Vigneau   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Decade of Innovation: Celebrating 10 Years of Cosmetics

It is with great pride and pleasure that we present this Special Issue, “Current and Future Trends in Cosmetics Research: The 10th Anniversary of Cosmetics”, marking a significant milestone–a decade of Cosmetics serving as a vibrant ...
Berardesca, Enzo, Enzo Berardesca
core   +1 more source

Improved Tactile Receptivity and Skin Beauty Benefits Through Topical Treatment with a Hyacinthus orientalis Bulb Extract Shown to Activate Oxytocin Receptor Signaling

Cosmetics
The neuropeptide oxytocin (OXT) is involved in social bonding, reproduction, and childbirth. Its activity is mediated by the oxytocin receptor (OXTR), also expressed in the skin.
Fabien Havas, Shlomo Krispin, Moshe Cohen, Joan Attia-Vigneau   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Machine learning unveils three layers of food complexity

npj Science of Food
Food is a more complex system than commonly perceived, comprising tens of thousands of molecules whose compositions and interactions ultimately shape human perception.
Qinfei Ke, Jingzhi Zhang, Xin Huang, Xingran Kou, Dachuan Zhang   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The mechanism of black ginseng extract in alleviating inflammatory aging

Journal of Dermatologic Science and Cosmetic Technology
Background: Black ginseng is a unique processed product of ginseng, a source of health food, medicine and modern cosmetics. Purpose: The purpose of this study was to develop a new application for preventing inflammatory aging.
Shaowei Yan, Chang Gao, Xinxu Rao, Lina Zuo, Qian Liu, Tingzhi Zhang   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Repeatable Perming via Thiol–Michael Click Reaction: Using Amide Derived from Maleic Acid and Cystine

Molecules
Conventional perming relies on oxidative agents that significantly damage hair. The thiol–Michael click perming strategy derived from linear aliphatic diols and diamines has been developed to avoid oxidative damage, but lacks repeatable perming ...
Zezhi Liu, Ling Ma, Timson Chen, Zhizhen Li, Ya Chen, Jinhua Li, Kuan Chang, Jing Wang   +7 more
doaj   +1 more source