Results 81 to 90 of about 64,617 (246)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Cosmetic Circumcision

open access: yesThe Journal of Sexual Medicine, 2013
A penile injection of 10–20 mcg prostaglandin E1 is given with a 31-gauge 8-mm needle at the beginning of the case to provide the patient with an erection. This helps the surgeon determine how much skin needs to be removed. While the penis remains erect, the foreskin is pulled over the glans penis, and released. The skin at the base of the penile shaft
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Protective Properties of Botanical Extracts against 5G Radiation-induced Damage to Human Skin, as Demonstrated in Preliminary Data from a Keratinocyte Cell Culture Model

open access: yesFrontiers in Bioscience-Landmark
Background: Next-generation 5G communication technology involves increasing use of 3–100 GHz wireless bands in population centers. Though still non-ionizing, this implies higher radiation energy vs. existing bands. The range is also shorter, needing more
Fabien Havas   +3 more
doaj   +1 more source

The Anti-Aging Potential of Extracts from Chaenomeles sinensis

open access: yesCosmetics, 2019
The Chaenomeles sinensis fruit is used as an effective antitussive agent, analgesic, and diuretic in traditional Chinese medicine. It has been reported that C. sinensis fruit extracts have antimicrobial and anti-inflammatory effects.
Shintaro Itoh   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Establishing a Purchasing Category to Optimize and Manage Contingent Workforce Spend : Case Company: Rituals Cosmetics Enterprise B.V [PDF]

open access: yes
This thesis investigates how to establish and optimize purchasing category for contingent workforce focusing on interim agency and freelancer spend at cosmetics retail company Rituals Cosmetics.
Obando, Tiina
core  

Natural Cosmetics

open access: yes, 2022
Diplomová práce pojednává o přírodní kosmetice, kterou se v posledních měsících kvůli svým dřívějším problémům s pletí detailněji zabývám. V teoretické části zmiňuji svůj příběh, který mě právě k tomuto tématu přivedl.
Tomčalová, Robina
core   +2 more sources

Clinical profiling of skin microbiome and metabolome during re-epithelialization

open access: yesScientific Reports
We investigated changes in skin microbiome and metabolome linked to wound healing and how these are affected by a formula known to improve re-epithelialization.
P. Bianchi   +14 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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