Results 81 to 90 of about 282,477 (312)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a Porphyridium Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract

open access: yesMarine Drugs
Red microalga Porphyridium cruentum produces a sulfated exopolysaccharide (EPS), which enables its survival in challenging intertidal and spray zones. Extracellular polysaccharide hyaluronic acid (HA) plays important roles in skin hydration, elasticity ...
Fabien Havas   +3 more
doaj   +1 more source

Nail cosmetics

open access: yesIndian Journal of Dermatology, Venereology, and Leprology, 2012
The nail as an anatomic structure protects the terminal phalanx of the digit from injury. Historically, it has served as a tool for protection and for survival. As civilizations developed, it attained the additional function of adornment. Nail beautification is a big industry today, with various nail cosmetics available, ranging from nail hardeners ...
Nina A, Madnani, Kaleem J, Khan
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Improved Tactile Receptivity and Skin Beauty Benefits Through Topical Treatment with a Hyacinthus orientalis Bulb Extract Shown to Activate Oxytocin Receptor Signaling

open access: yesCosmetics
The neuropeptide oxytocin (OXT) is involved in social bonding, reproduction, and childbirth. Its activity is mediated by the oxytocin receptor (OXTR), also expressed in the skin.
Fabien Havas   +3 more
doaj   +1 more source

The Anti-Aging Potential of Extracts from Chaenomeles sinensis

open access: yesCosmetics, 2019
The Chaenomeles sinensis fruit is used as an effective antitussive agent, analgesic, and diuretic in traditional Chinese medicine. It has been reported that C. sinensis fruit extracts have antimicrobial and anti-inflammatory effects.
Shintaro Itoh   +3 more
doaj   +1 more source

COMPETITIVENESS AND PERFORMANCE ON THE COSMETICS MARKET [PDF]

open access: yes
Most organizations are going through massive changes. Their customers are changing, their competition is changing, their customerâ€(tm)s needs are changing and their resources availability is changing - the cosmetics companies are no different ...
Bagu Constantin   +3 more
core  

The Impact of Experiential Augmented Reality Applications on Fashion Purchase Intention [PDF]

open access: yes, 2018
Utilizing the stimulus-organism-response (SOR) model, the purpose of this study is to examine the effects of augmented reality (AR) (specifically augmentation) on consumers’ affective and behavioral response and to assess whether consumers’ hedonic ...
Alexander, Bethan   +2 more
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Machine learning unveils three layers of food complexity

open access: yesnpj Science of Food
Food is a more complex system than commonly perceived, comprising tens of thousands of molecules whose compositions and interactions ultimately shape human perception.
Qinfei Ke   +4 more
doaj   +1 more source

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