Summary: Peripheral pharmacology of cough
Hypersensitivity of the 'cough receptors' is one of the primary causes of uncontrollable and nonproductive cough. These receptors are therefore the logical targets in developing antitussive therapeutics.
Page, C, Lee, L Y
core +2 more sources
ATP cough challenge as a novel diagnostic tool to assess cough hypersensitivity
Background: Refractory chronic cough (RCC) is a diagnosis of exclusion, with no widely used clinical test to assess cough hypersensitivity syndrome. Adenosine 5’-triphosphate (ATP) activates purinergic receptors on airway sensory nerves and can provoke ...
Ryan Singer +8 more
core +1 more source
Cerebellar ataxia, neuropathy and vestibular areflexia syndrome: a neurogenic cough prototype
Chronic cough is a frequent disorder that is defined by cough of more than 8 weeks duration. Despite extensive investigation, some patients exhibit no aetiology and others do not respond to specific treatments directed against apparent causes of cough ...
Laurent Guilleminault +5 more
doaj +1 more source
Pulmonary IFN-γ Causes Lymphocytic Inflammation and Cough Hypersensitivity by Increasing the Number of IFN-γ-Secreting T Lymphocytes. [PDF]
Deng Z +5 more
europepmc +1 more source
Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms. [PDF]
Cheng J +7 more
europepmc +1 more source
Managing patients with chronic cough: challenges and solutions
Jeanne-Marie Perotin,1,2 Claire Launois,1 Maxime Dewolf,1 Antoine Dumazet,1 Sandra Dury,1 François Lebargy,1 Valérian Dormoy,2 Gaëtan Deslee1,2 1Department of Respiratory Diseases, University Hospital of Reims, Reims, France; 2INSERM ...
Launois C +7 more
core
Future Directions in Treating Cough
Cough is a common and troublesome symptom that can be difficult to treat. New therapeutic options that are safe and more effective than those currently available are needed. In this article, the authors offer opinion on future directions in the treatment
Elder, J. +3 more
core +1 more source
Chili Pepper Molecule as Potential Treatment for Cough Hypersensitivity Syndrome
Approximately 20% of patients with chronic cough, or cough that lasts greater than 8 weeks, do not respond to medical intervention and are said to have refractory chronic cough (RCC).
Campbell, Sarah
core
Editorial: Neural and Mechanical Mechanisms in Pulmonary Defense: What Does the Future Hold?
Nicolle J. Domnik +6 more
doaj +1 more source
Recurrent pneumonitis in a 10-year-old girl with pigeon breeder's disease
Hypersensitivity pneumonitis is an allergic disease resulting from sensitization to inhaled organic dust, usually manifest with recurrent bouts of cough, dyspnea and fever. Most of the reported cases concern the adult population.
E Dilber +4 more
doaj

