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Cough and cough hypersensitivity as treatable traits of asthma

The Lancet Respiratory Medicine, 2023
Cough is a common and troublesome symptom in people with asthma and is often associated with poorer asthma control and exacerbations. Apart from asthma, other causes or comorbidities might underlie cough in asthma, such as rhinosinusitis and bronchiectasis.
Lai, Kefang   +8 more
openaire   +5 more sources

Eight International London Cough Symposium 2014: Cough Hypersensitivity Syndrome as the Basis for Chronic Cough

open access: yesPulmonary Pharmacology and Therapeutics, 2015
At the Eighth International London Cough Conference held in London in July 2014, the focus was on the relatively novel concept of cough hypersensitivity syndrome (CHS) as forming the basis of chronic cough.
Kian Fan Chung   +2 more
exaly   +2 more sources

Mucus Transpiration as the Basis for Chronic Cough and Cough Hypersensitivity

Lung, 2023
Chronic cough is characterized by a state of cough hypersensitivity. We analyze the process of transpiration, by which water appears to evaporate from laryngeal and tracheal mucus as from the surface of a leaf, as a potential cause of cough hypersensitivity.
David A, Edwards, Kian Fan, Chung
openaire   +2 more sources

Cough Reflex Hypersensitivity as a Key Treatable Trait [PDF]

open access: yesJournal of Allergy and Clinical Immunology: in Practice
Cough reflex hypersensitivity is emerging as a key treatable trait in chronic cough and other cough-associated respiratory conditions. This review examines the neurological basis of cough, highlighting the complex interplay between peripheral and central
Woo-Jung Song   +2 more
exaly   +2 more sources

Cough Reflex Hypersensitivity: A Role for Neurotrophins

open access: yesExperimental Lung Research, 2017
Cough is one of the most common complaints for which sufferers seek medical assistance. However, currently available drugs are not very effective in treating cough, particularly that which follows an upper respiratory tract infection. Nonetheless, there has been a significant increase in our understanding of the mechanisms and pathways of the defensive
Sahar M Jaffal, Ahmed Z El-Hashim
exaly   +3 more sources

Laryngeal Hypersensitivity in Chronic Cough

Pulmonary Pharmacology and Therapeutics, 2015
Patients with chronic cough often report symptoms arising in the throat, in response to non-specific stimuli. Accordingly, the concept of a 'hypersensitivity' of the larynx in chronic cough has evolved over the past ten years. Patients with cough and laryngeal hypersensitivity frequently report features that overlap other laryngeal dysfunction ...
J H, Hull, A, Menon
exaly   +3 more sources

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