Results 81 to 90 of about 155,291 (181)
European Journal of Haematology, EarlyView.ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
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Central mechanisms of airway sensation and cough hypersensitivity [PDF]
Pulmonary Pharmacology & Therapeutics, 2017 The airway sensory nervous system is composed of two anatomically distinct processing pathways that allow for the production of respiratory reflexes and voluntary evoked respiratory behaviours in response to sensing an airway irritation. Disordered sensory processing is a hallmark feature of many pulmonary disorders and results in the development of ...
Alexandria K. Driessen +6 more
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, 2021 Purpose: Recent evidence suggests that cough hypersensitivity may be a common feature of chronic cough in adults. However, the clinical relevance remains unclear.
김민혜
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, 2016 Introduction: Chronic non-productive coughing is a major complication of pulmonary disease and can also occur in many individuals without identifiable underlying pathology. The common clinical link in patients with cough is an enhanced sensitivity of the
Irving, Louis +5 more
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Chronic Refractory Cough: A Disorder of the Brain and the Respiratory System (Editorial)
, 2022 Chronic refractory cough (CRC) increasingly is recognised as a distinct clinical entity; cough that persists despite addressing potential aggravating factors (eg, asthma, acid reflux, angiotensin-converting enzyme medication).1 CRC is associated with ...
Cho, PSP, Turner, RD
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Skin hypersensitivity in chronic cough patients: symptom profiles and psychosomatic correlates
Annals of MedicineBackground Cough hypersensitivity syndrome (CHS) is a characteristic of patients with chronic cough (CC). Sensitive skin syndrome (SSS), which is characterised by cutaneous pain and pruritus, may share neural hypersensitivity mechanisms with CHS.
Tongyangzi Zhang +11 more
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The Journal of Physiology, EarlyView.Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
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Is Laryngeal Hypersensitivity the Basis for Cough Hypersensitivity in Chronic Cough? [PDF]
D93. EVALUATION AND NOVEL TREATMENT APPROACH FOR CHRONIC COUGH, 2020 A. Stark, M. Wright, K. Sundar
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High‐altitude headache: Insights into pathophysiology and potential treatment implications
The Journal of Physiology, EarlyView.Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla +3 more
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The Journal of Physiology, EarlyView.Abstract figure legend A preclinical large‐animal model of hypertensive heart failure with preserved ejection fraction (HFpEF) was used to examine the role of purinergic P2X3 receptor signalling during treadmill exercise. Animals were instrumented with either thoracic cardiac output and coronary flow probes or abdominal renal and hindlimb blood flow ...
Mridula Pachen +7 more
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