Results 41 to 50 of about 43,230 (246)
Small‐Molecule Activation of mRNA Translation by Click‐to‐Release Reaction in Cells
Angewandte Chemie, EarlyView.A new method to control mRNA activity using bioorthogonal click‐to‐release reactions is presented. The 5′ cap is modified with a trans‐cyclooctene (TCO) that quickly reacts with hydroxyaryl‐tetrazines and efficiently releases the native cap 0. TCO‐capped mRNAs are initially translationally inactive but can be activated with non‐toxic, cell‐permeable ...
Tess Vosman +5 more
wiley +2 more sources
Frontiers in Cellular and Infection MicrobiologyCoumarin, a phenolic compound, is a secondary metabolite produced by plants such as Tanga and Lime. Coumarin derivatives were prepared via Pechmann condensation.
Hui-su Jung +8 more
doaj +1 more source
New natural deep eutectic solvents based on aromatic organic acids
Green Chemistry Letters and Reviews, 2021 It is imminent to explore new types of starting materials for natural deep eutectic solvents (NADESs). Herein, a series of natural aromatic organic acids as the hydrogen bond donor (HBD) and coumarin as the model hydrogen bond acceptor (HBA) were used to
Yuhang Shan +4 more
doaj +1 more source
Do's and Don'ts When Visiting Circularly Polarized Luminescence
Advanced Optical Materials, EarlyView.This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
Wash‐Free Multi‐Target Super‐Resolution Microscopy With Photocaged DNA Labels
Angewandte Chemie, EarlyView.Photocaged DNA labels enable wash‐free multi‐target super‐resolution microscopy. A single type of DNA–fluorophore imager strand hybridizes to two orthogonal light‐responsive docking strands, whose hybridization state can be modulated with light from “ON” to “OFF” and vice versa.
Nina Kaltenschnee +6 more
wiley +2 more sources
Influence of Polarity of Solvents on the Spectral Properties of Bichromophoric Coumarins
Molecules, 2010 Absorption and fluorescence spectra of bichromophoric coumarins were investigated in different solvents and in polymer matrices. These bichromophoric coumarins were composed of a coumarin dimethylamino-substituted at position 7 or unsubstituted coumarin ...
Henrieta Stankovicova +3 more
doaj +1 more source
Advanced Science, EarlyView.The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.This minireview highlights recent advances in catalyst development and mechanistic strategies that enable photochemical and photocatalytic reactivity under 700–1000 nm NIR light, emphasizing how long‐wavelength excitation expands opportunities in both synthetic chemistry and biology.
Santosh K. Pagire +3 more
wiley +2 more sources
E-Journal of Chemistry, 2004 As a target to synthesize various Thiazolidinone derivatives, 2-Amino-4-(coumarin-3-yl)-thiazole has been prepared by the reactions of 3-Bromo acetyl coumarin with thiourea. 3-Bromo acetyl coumarin was prepared from 3-Acetyl coumarin.
B. D. Naik, K. R. Desai
doaj +1 more source
Advanced Science, EarlyView.A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source