Results 51 to 60 of about 71,972 (342)
Asymmetrical hybridization and gene flow between Eisenia andrei and E. fetida lumbricid earthworms [PDF]
Uniformly pigmented Eisenia andrei (Ea) and striped E. fetida (Ef) lumbricid earthworms are hermaphrodites capable of self-fertilization, cross-fertilization, and asymmetrical hybridization.
Bigaj, Janusz +3 more
core +1 more source
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang +12 more
wiley +1 more source
Switchable Coumarins for Ratiometric pH Sensing
A fluorescent chromophore and a pH-sensitive heterocycle were integrated within a single covalent skeleton to generate four molecular switches with ratiometric fluorescence response.
Mercedes M. A. Mazza +7 more
doaj +1 more source
Effect of sensitization on the electrochemical properties of nanostructured NiO [PDF]
Screen-printed NiO electrodes were sensitized with 11 different dyes and the respective electrochemical properties were analyzed in a three-electrode cell with the techniques of cyclic voltammetry and electrochemical impedance spectroscopy.
Barolo, Claudia +3 more
core +1 more source
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source
Grapefruit is one of the most popular Citrus fruits, which is beneficial for health. Coumarins are the main secondary metabolites in grapefruits. The structural and functional diversity makes the comprehensive determination of coumarins in complex system
Shilin Gong +7 more
doaj +1 more source
Coumarin: a novel player in microbial quorum sensing and biofilm formation inhibition [PDF]
Antibiotic resistance is a growing threat worldwide, causing serious problems in the treatment of microbial infections. The discovery and development of new drugs is urgently needed to overcome this problem which has greatly undermined the clinical ...
Gutiérrez-Barranquero, José A. +3 more
core +2 more sources
One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu +8 more
wiley +1 more source
Mapping the Biotransformation of Coumarins through Filamentous Fungi
Natural coumarins are present in remarkable amounts as secondary metabolites in edible and medicinal plants, where they display interesting bioactivities.
Jainara Santos do Nascimento +5 more
doaj +1 more source
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang +23 more
wiley +1 more source

