Coumarins and P450s, Studies Reported to-Date
Cytochrome P450 enzymes (CYPs) are important phase I enzymes involved in the metabolism of endogenous and xenobiotic compounds mainly through mono-oxygenation reactions into more polar and easier to excrete species.
Maryam Foroozesh +3 more
doaj +1 more source
Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]
This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H. +6 more
core +3 more sources
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale +8 more
wiley +1 more source
Synthesis and complete NMR spectral assignments of new benzylamino coumarin derivative [PDF]
This research involves the reaction of 4-chloro-3-nitrocoumarin and (4-methoxyphenyl)methanamine, whereby a novel coumarin derivative 4-[(4-methoxybenzyl) amino]-3-nitro-2H-chromen-2-one was obtained in good yield.
Dekić Vidoslav +4 more
doaj
A Family of Styrylcoumarins: Synthesis, Spectroscopic, Photophysical and Photochemical Properties [PDF]
A new family of 5-styrylcoumarins exhibit E–Z isomerization around the Cα[DOUBLE BOND]Cβ bond with large extinction coefficients, medium-lived excited states, and moderate fluorescence quantum yields (see picture).
Borges +21 more
core +1 more source
Genetic code expansion for chemosensing and chemical actuation of biological functions
Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley +1 more source
Effects of Osthol Isolated from Cnidium monnieri Fruit on Urate Transporter 1
(1) Background: Crude drugs used in traditional Japanese Kampo medicine or folk medicine are major sources of new chemical entities for drug discovery.
Yuusuke Tashiro +7 more
doaj +1 more source
Organic Food and Health: A new project to study the effects of plant cultivation methods (organic and conventional) on nutritional value, health and reproduction in an animal experiment [PDF]
Many consumers believe that food from plants grown under certain conditions, such as organic agriculture, will benefit health more than conventional food.
Andersen, Jens-Otto +9 more
core
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin +7 more
wiley +1 more source
Parvovirus B19 (B19V) is a human pathogenic virus associated with a wide range of clinical conditions. Currently, there are no recognized antiviral drugs for B19V treatment; therefore, efforts in the search for compounds inhibiting B19V replication are ...
Ilaria Conti +6 more
doaj +1 more source

