Results 81 to 90 of about 24,198 (212)

Isodesmic Supramolecular Assembly of Phenylethynylene Bis‐Urea Macrocycles

Chemistry – A European Journal, EarlyView.
A soluble phenylethynylene bis‐urea macrocycle assembles in polar media via an isodesmic hydrogen bonded mechanism. Spectroscopic and morphological studies reveal nanoscale aggregates with short chain length, while guest additives modulate enthalpy and polymerization, demonstrating tunable supramolecular assembly.
Fahidat A. Gbadamosi, Kazi Md Zubaer, Vaibhavi A. Samant, Jillian Eubanks, Sophya Garashchuk, Linda S. Shimizu   +5 more
wiley   +1 more source

Anti-inflammatory and cytotoxic effects of Jatropha podagrica extracts on skin cancer

Research in Pharmaceutical Sciences
Background and purpose: Jatropha podagrica Hook, belongs to the Euphorbiaceae family, which possesses anticancer activities and is traditionally applied to treat skin diseases. No reports of J. podagrica anti-neoplastic activity on an amelanotic melanoma
Reawfang Sriyom, Arunporn Itharat, Onmanee Prajuabjinda, Pakakrong Thongdeeying, Srisopa Ruangnoo, Sunita Makchuchit, Pranporn Kuropakornpong, Kanyarat Namphonsaen, Perika Monkanna, Neal M. Davies   +9 more
doaj   +1 more source

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

2-Oxo-2H-chromen-7-yl pentanoate

IUCrData
In the title compound, C14H14O4, the dihedral angle between the coumarin nucleus and the pentanoate moiety is 62.20 (7)°. The coumarin moiety is planar as usual, with a maximum deviation from the least-squares plane of 0.081 (2) Å.
A. J. N'Gouan, H. Bazié, S. D. Goulizan Bi, A. Djandé, R. Kakou-Yao, C. Lecomte   +5 more
doaj   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source

Pharmaco-Toxicological Effects of Cachrys libanotis Extract: Antioxidant, Antimicrobial, and Cytotoxic Activities in Human Cell Lines and Embryonic Models

Antioxidants
We conducted a study to explore the potential of an enriched coumarin extract from Cachrys libanotis for the prevention and treatment of various diseases.
Mary Fucile, Ioana Gabriela Macasoi, Monica Negrea, Diana Obistioiu, Mariangela Marrelli, Ersilia Alexa, Cristina Dehelean, Giancarlo Statti, Filomena Conforti, Iulia Pinzaru   +9 more
doaj   +1 more source

Dual‐Stabilized Single‐Site Fe(II) for Catalytic Conversion of CO2 to Propiolic Acid Under Ambient Condition

EcoEnergy, EarlyView.
We develop a highly cost‐effective heterogeneous catalyst for efficient CO2 conversion to propiolic acid under mild conditions via a nano‐confined approach with porous MIL support. ABSTRACT Efficient conversion of carbon dioxide to organics has been a promising outlet for value‐added carbon dioxide consumption.
Bin Lei, Zhenzhen Zhou, Xiao Liu, Bo Li, Wenyuan Wang, Jian‐Gong Ma, Peng Cheng   +6 more
wiley   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

ESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio, Cristiano Amarelli, Rosaria Chiappetti, Irene Mattucci, Veronica Flocco, Mahmoud Issa Rammal, Ciro Abete, Francesca Mazzella, Ciro Maiello, Pasquale Abete, Francesco Cacciatore   +10 more
wiley   +1 more source

Design, Synthesis, and Photophysical Studies of Functionalized Polyaromatic Isonitriles as Visible Light Photoredox Catalysts

European Journal of Organic Chemistry, EarlyView.
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini, Camilla Russo, Jussara Amato, Carmine Volpe, Francesca Brunelli, Laurence Grimaud, Maxime R. Vitale, Greta Donati, Andrea Basso, Mariateresa Giustiniano   +9 more
wiley   +1 more source

Antimicrobial properties of Fomitopsis officinalis in the light of its bioactive metabolites: a review

Mycology, 2019
Fomitopsis officinalis, also known as Laricifomes officinalis, is a medicinal polypore used for millennia (Agarikon) to contrast several diseases, particularly the pulmonary ones.
Carolina Girometta
doaj   +1 more source