Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Clubs within clubs: The Council of the Baltic Sea States (CBSS) and the Benelux as Macro-regions within the EU [PDF]
, 2011 This paper deals with two examples of macro-regions in the EU: the Benelux and the Council of the Baltic Sea States (CBSS). Building on the distinction between “old” and “new” regionalism, it discusses some characteristics of regions in general, and of ...
Groenendijk, Nico
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Membership in multilateral environmental agreements and global security challenges [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2017 The paper points to the relations between multilateral environmental agreements (MEAs) with global characteristics and contemporary security problems.
Todić Dragoljub C.
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Influence of Regional Governments on National Positions in the Council of the EU
Czech Journal of International Relations, 2016 In spite of the fact that some EU member states are fully-fledged federations, some are centralized and many lie somewhere in between these two poles, EU perceives its constituent countries as unitary, indivisible actors.
Pavel Dvořák, Markéta Pitrová
doaj
Reform of the EU Institutions: Implications for the EU’s Performance in Climate Negotiations. CEPS Policy Brief No. 40, September 2003 [PDF]
, 2003 This CEPS Policy Brief assesses the potential impact of the draft Constitutional Treaty of the Convention on the Future of Europe on the way the EU operates in international climate negotiations. Although Treaty revisions in the EU are ultimately decided
Egenhofer, Christian. +1 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The emergence of European political foundations: Political entrepreneurs and transnational transfers. GSPE Working Paper 05/29/2009 [PDF]
, 2009 Recently, the European Commission has made some significant steps towards the recognition of political party foundations at EU level. Firstly, it has agreed to acknowledge the political foundations as actors of European development policies. Secondly, it
Dakowska, Dorota.
core
Embedding the 'new economy' in Europe : a study in the institutional specificities of knowledge-based growth [PDF]
, 2001 Aspirations for a 'new economy' currently feature prominently in the economic policy debate within the EU. So pronounced is elite interest in the 'new economy' that the issue of knowledge-based growth dominated the Special European Council organized for ...
Watson, Matthew
core +1 more source