Results 51 to 60 of about 77,892 (271)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Enhancing choice? The role of technology in the career support market [PDF]
, 2010 This report explores the role that technology has played in the development of the career support market. This market is conceived broadly to include all possible resources that individuals might draw upon to support them in their career development.
Hooley, Tristram +2 more
core +1 more source
Ecojusticia, equidad y ética: retos para la orientación educativa y profesional [PDF]
, 2019 In social and environmental terms we live in precarious and uncertain times, where not only the sustainability of the planet rests in the balance, but also that of human existence.
Irving, Barrie A. +1 more
core +2 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
STEM subjects and jobs: a longitudinal perspective of attitudes among Key Stage 3 students, 2008 - 2010 [PDF]
, 2011 The STEM Careers Awareness Timelines initiative was part of Action Programme 8 which ran between 2008 to 2011. The project was undertaken by the Centre for Education and Industry at the University of Warwick, the International Centre for Guidance Studies
Bentley, Kieran, Hutchinson, Jo
core +1 more source
‘If you look the part you’ll get the job’: should career professionals help clients to enhance their career image? [PDF]
, 2014 This article presents a critical exploration of the role of career professionals in supporting people to reflect on and enhance their appearance, attractiveness and self-presentation (career image).
Barnard M. +18 more
core +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A review of mentorship measurement tools [PDF]
, 2016 © 2016 Elsevier Ltd. Objectives: To review mentorship measurement tools in various fields to inform nursing educators on selection, application, and developing of mentoring instruments. Design: A literature review informed by PRISMA 2009 guidelines. Data
Chen, Yanhua +2 more
core +1 more source
CAREER COUNSELLING: A CONSTRUCTIVE INTERACTION BETWEEN SCIENCE AND PRACTICE
Професійна педагогіка, 2019 The article analyzes the current status of student counselling in vocational education institutions, contextualizes findings on this problem and discloses contradictory points of counselling. It is justified that vocational education institutions normally view professional career counselling as the processes of dealing with and solving students ...
Liudmyla Bazyl, Valerii Orlov
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source