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Chiral Separation by Counter-Current Chromatography

TrAC - Trends in Analytical Chemistry, 2015
Counter-current chromatography (CCC) is a new, efficient, productive chromatographic technique based on continuous liquid-liquid partition. Recently, it attracted more attention in chiral separation due to its high load capacity, cheap liquid stationary phase and low solvent consumption, when compared to traditional chiral separation techniques.
Xin-Yi Huang, Duo-Long Di
exaly   +2 more sources

Enantioseparations in Counter-Current Chromatography and Centrifugal Partition Chromatography

Journal of Chromatography A, 2001
Examples of chiral separations in counter-current chromatography (CCC) and centrifugal partition chromatography (CPC) are not numerous, due to the difficulty of finding chiral selectors highly selective in the liquid phase as well as a combination of solvents that does not destroy the selectivity and retains the capacity to elute chiral isomers of ...
exaly   +3 more sources

Analysis of New Counter-Current Chromatography Operating Modes

Journal of Chromatography A, 2007
Some novel cyclic operating modes of counter-current chromatography have been suggested. Chromatographic separation processes with two zones of different partition coefficients and with extraction and scrubbing (washing) zones are mathematically described using the eluting counter-current distribution approach. Two possible cyclic modes of dual counter-
Andrey Voshkin
exaly   +3 more sources

Two-dimensional counter-current chromatography: 1st Traditional counter-current chromatography, 2nd acid–base elution counter-current chromatography

Journal of Chromatography A, 2011
An on-line column-switching counter-current chromatography (CCC) with solid-phase trapping interphase is presented in this paper. The large volume injection is avoided using solid-phase trapping interphase. Thereby, totally different chemical composition biphasic solvent system can be utilized to enhance system orthogonality. In the present work, a 140
Ruilin, Hu   +4 more
openaire   +2 more sources

Separation of acetins by counter‐current chromatography

Journal of Separation Science, 2011
AbstractIn this work we report the purification of a crude acetin mixture into mono‐, di‐ and triacetin by countercurrent chromatography. The process was initially tested on a small, semi‐preparative scale (0.5 g) to determine its efficiency. The process was then scaled up to accommodate 2.5 g of crude reaction products containing a mixture of the ...
Bruno Amaral, Meireles   +3 more
openaire   +2 more sources

Counter-current chromatography.

Journal of chromatography, 1991
Abstract The simplicity of counter-current chromatography (CCC) is sometimes overshadowed by a complex description of its mechanical and chromatographic attributes. The universal features of chromatographic theory relevant to CCC are summarized here, using a partition coefficient elution scale to present th chromatogram in a general, readily ...
openaire   +3 more sources

Counter-Current Chromatography

1986
Counter-current chromatography is characterised by the absence of a solid support, the factor which provides the most important advantage of this separation technique. Solutes are readily retained by solid supports and these adsorption effects are often manifested by elution curves which show tailing of the substances under consideration.
Kurt Hostettmann   +2 more
openaire   +1 more source

Universal counter-current chromatography modelling based on counter-current distribution

Journal of Chromatography A, 2009
There is clearly a need for a model which is versatile enough to take into account the numerous operating modes and pump out procedures that can be used with counter-current chromatography (CCC). This paper will describe a universal model for counter-current chromatography based on counter-current distribution.
Joost, de Folter, Ian A, Sutherland
openaire   +2 more sources

Isolation and Purification of the Bioactive Carotenoid Zeaxanthin From the Microalga Microcystis aeruginosa by High-Speed Counter-Current Chromatography

open access: yesJournal of Chromatography A, 2005
High-speed counter-current chromatography was successfully applied for the first time to the isolation and purification of the bioactive carotenoid zeaxanthin from the cyanobacterium Microcystis aeruginosa. The crude zeaxanthin was obtained by extraction
Hua-Bin Li, Ricky Ngok-Shun Wong
exaly   +2 more sources

Evaluation of dual flow counter-current chromatography and intermittent counter-current extraction

Journal of Chromatography A, 2011
The aim of this research is to compare two continuous extraction technologies, intermittent counter-current extraction (ICcE) and dual flow counter-current chromatography (DFCCC), in terms of loading and throughput using the GUESSmix, and show the advantages and disadvantages of the two methods.
Svetlana, Ignatova   +3 more
openaire   +2 more sources

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