Results 141 to 150 of about 8,771,743 (176)

How to achieve rapid separations in counter-current chromatography

Journal of Chromatography A, 2006
A new generation of high performance coil planet centrifuges is now making it possible to realize the enormous potential of liquid-liquid partition chromatography for the rapid and predictable scale up of separation processes. This paper uses a separation of flavonoids to demonstrate how rapid fractionations can be obtained at high flow rates with ...
Lijuan, Chen, Ian A, Sutherland
openaire   +2 more sources

Developments in the application of counter-current chromatography to plant analysis

Journal of Chromatography A, 2006
Counter-current chromatography is a very versatile separation technique which does not require a solid stationary phase. It relies simply on the partition of a sample between the two phases of an immiscible solvent system. Some of the more recent applications of the method to the separation of plant-derived natural products are described here.
Marston, Andrew, Hostettmann, Kurt
openaire   +4 more sources

Modelling counter-current and dual counter-current chromatography using longitudinal mixing cell and eluting counter-current distribution models

Journal of Chromatography A, 2007
Two well known approaches are considered to analyze the processes of counter-current and dual counter-current chromatography: the longitudinal mixing cell model and the Craig's counter-current distribution model. The cell model represents perfectly mixed, equally sized cells in series.
Artak E, Kostanyan, Vera V, Belova, Anatoly I, Kholkin   +2 more
openaire   +2 more sources

Recent progress in separation prediction of counter‐current chromatography

Journal of Separation Science, 2020
AbstractAs a liquid‐liquid partition chromatography, counter‐current chromatography has advantages in large sample loading capacity without irreversible adsorption, which has been widely applied in separation and purification fields. The main factors, including partition coefficient, two‐phase solvent systems, apparatus, and operating parameters ...
Yuru Guo, Shengqiang Tong, Keqing Zhang, Jizhong Yan   +3 more
openaire   +2 more sources

Chromatography of peptides on a multi-coil counter-current chromatograph

Journal of Chromatography A, 1989
A modified horizontal flow-through coil planet centrifuge has been constructed that has the potential for preparative chromatography. The multi-coil counter-current chromatograph, equipped with a set of four multi-layer coils, has have improved performance with polar solvents suitable for peptide elution.
M, Knight, Y, Ito
openaire   +2 more sources

Counter-current chromatography: Simple process and confusing terminology

Journal of Chromatography A, 2011
The origin of counter-current chromatography is briefly stated, followed by a description of the mechanism of elution of solutes, which illustrates the elegance and simplicity of the technique. The CCC retention equation can be mentally derived from three facts; that a substance with a distribution coefficient of 0 elutes at the mobile phase solvent ...
openaire   +2 more sources

High-speed counter-current chromatography of apple procyanidins

Journal of Chromatography A, 2000
Apple procyanidins were separated by high-speed counter-current chromatography using a type-J multilayer coil planet centrifuge. Several two-phase solvent systems with a wide range of hydrophobicities from a non-polar hexane system to polar n-butanol systems were evaluated their performance in terms of the partition coefficient and the retention of the
Y, Shibusawa, A, Yanagida, A, Ito, K, Ichihashi, H, Shindo, Y, Ito   +5 more
openaire   +2 more sources

Advantages of a small-volume counter-current chromatography column

Journal of Chromatography A, 2009
Counter-current chromatography (CCC) works with a support-free liquid stationary phase. This allows for preparative separations and purifications. However, there are serious technical constraints because of the need to keep a liquid stationary phase in a column. Centrifugal fields are used.
Alain, Berthod, Svetlana, Ignatova, Ian A, Sutherland   +2 more
openaire   +2 more sources

Thin layer chromatography and counter-current analysis in porphyrias

British Journal of Dermatology, 1975
The porphyrin metabolism of 100 patients with porphyria and 351 of their relatives has been studied. Thin layer chromatography of methyl esters of the urinary porphyrin was undertaken in sixty-six patients with different types of porphyria, and forty-five relatives, seventeen patients with hepatic cirrhosis, three patients with lead poisoning and ...
J P, Aguadé, C, Herrero, J, Almeida, S G, Smith, R V, Belcher   +4 more
openaire   +2 more sources

Separations of hydrophobic synthetic peptides in counter-current chromatography

Journal of Chromatography A, 2007
Synthetic peptides with many aromatic, aliphatic and especially acidic amino acid residues are not very soluble and require strong solvents for useful partitioning. A chloroform-methanol-acidic solvent system fractionates neutral and basically charged 26-mers to provide high yields.
openaire   +2 more sources