Results 41 to 50 of about 43,242 (248)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Transient rotation of photospheric vector magnetic fields associated with a solar flare

open access: yesNature Communications, 2018
The violent solar eruptions known as flares are caused by magnetic reconnection. Here, the authors identify a sudden 12°–20° counter clockwise rotation of vector magnetic fields in photosphere, associated with the emissions of moving flare ribbons.
Yan Xu   +9 more
doaj   +1 more source

Substrate Effect on Catalytic Loop and Global Dynamics of Triosephosphate Isomerase

open access: yesEntropy, 2013
The opening/closure of the catalytic loop 6 over the active site in apo triosephosphate isomerase (TIM) has been previously shown to be driven by the global motions of the enzyme, specifically the counter-clockwise rotation of the subunits. In this work,
Pemra Doruker, Zeynep Kurkcuoglu
doaj   +1 more source

Dark state with counter-rotating dissipative channels

open access: yesScientific Reports, 2017
AbstractDark state as a consequence of interference between different quantum states has great importance in the fields of chip-scale atomic clock and quantum information. For the Λ-type three-level system, this dark state is generally regarded as being dissipation-free because it is a superposition of two lowest states without dipole transition ...
Zheng-Yang Zhou   +4 more
openaire   +4 more sources

On generating counter-rotating streamwise vortices [PDF]

open access: yesIOP Conference Series: Materials Science and Engineering, 2015
Counter-rotating streamwise vortices are known to enhance the heat transfer rate from a surface and also to improve the aerodynamic performance of an aerofoil. In this paper, some methods to generate such counter-rotating vortices using different methods or physical conditions will be briefly considered and discussed.
S H Winoto   +7 more
openaire   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Counter-Rotation in Disk Galaxies

open access: yes, 2014
Counter-rotating galaxies host two components rotating in opposite directions with respect to each other. The kinematic and morphological properties of lenticulars and spirals hosting counter-rotating components are reviewed. Statistics of the counter-rotating galaxies and analysis of their stellar populations provide constraints on the formation ...
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Different mechanisms contributing to savings and anterograde interference are impaired in Parkinson’s disease

open access: yesFrontiers in Human Neuroscience, 2013
Reinforcement and use-dependent plasticity mechanisms have been proposed to be involved in both savings and anterograde interference in adaptation to a visuomotor rotation (c.f.Huang et al., 2011).
Li-Ann eLeow   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy