Results 71 to 80 of about 8,192,067 (257)

Study of MHD on porous flat and curved circular plate lubricated with couple stress fluid-a slip velocity model

open access: yesResults in Engineering
The current study achieved to explore novel of curved circular and porous flat plate under the existence of MHD and slip velocity. The gap between the plates is filled with conducting non-Newtonian lubricant as a couple stress fluids.
Umadevi Devani   +7 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Size-dependent vibration analysis of graphene-PMMA lamina based on non-classical continuum theory

open access: yesScience and Engineering of Composite Materials, 2019
This paper studies the free vibration of polymer nanocomposite reinforced by graphene sheet. In this work, the new size dependent formulation is presented for nanocomposites based on couple stress theory.
Zeverdejani Mehran Karimi   +1 more
doaj   +1 more source

Free vibration and buckling analyses of a size-dependent axially functionally graded beam incorporating transverse shear deformation

open access: yesResults in Physics, 2017
A new size-dependent axially functionally graded (AFG) beam model with transverse shear deformation is proposed based on the modified couple stress theory (MCST).
Wanli Yang, Dan He
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Reflection and transmission at the boundary surface of modified couple stress thermoelastic media [PDF]

open access: yes, 2016
In this paper the reflection and transmission at a plane interface in modified couple stress generalized thermoelastic solid half spaces in the context of Loard-Shulman (LS) and Green-Lindsay (GL) theories in welded contact are investigated.
R. Kumar, Kumar, K., Kumar, R., K. Kumar
core   +1 more source

Effect of Pressure Dependent Viscosity on Couple Stress Squeeze Film Lubrication between Rough Parallel Plates

open access: yesTribology Online, 2015
In this paper, a theoretical study of the effect of pressure dependent viscosity on couple stress squeeze film lubrication between rough parallel plates is analyzed on the basis of Barus experimental results.
Neminath Bujappa Naduvinamani   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Effects of Couple Stress on the Growth Rate of Rayleigh- Taylor Instability at the Interface in a Finite Thickness Couple Stress Fluid

open access: yesJournal of Applied Fluid Mechanics, 2010
In this paper the effects of couple stress fluid on the control of Rayleigh-Taylor instability at the interface between a dense fluid accelerated by a lighter fluid is studied. A simple theory, based on fully developed approximations, is used to derive
N. Rudraiah, G. Chandrashekara
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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