Results 101 to 110 of about 535,578 (267)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Numerical modelling of heat generated by electroosmotic flows in micro-channels [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +2 more
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Mathematical and Numerical Analysis of a Pair of Coupled Cahn-Hilliard Equations with a Logarithmic Potential [PDF]
, 2010 Mathematical and numerical analysis has been undertaken for a pair of coupled Cahn-Hilliard equations with a logarithmic potential and with homogeneous Neumann boundary conditions. This pair of coupled equations arises in a phase separation model of thin
AL-GHAFLI, AHMED,ALI,M
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Facile method for CLSM imaging unfunctionalized Au nanoparticles through fluorescent channels [PDF]
, 2009 The microscopic visualization of metal nanoparticles has become a useful tool for the investigation of their applications in cell labeling and the study of their bio-effects.
Chen, Yueyue +7 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Mechanism of elastic scattering of 7Li, 7Be + 9Be nuclei and optical potentials of their interaction [PDF]
Ядерна фізика та енергетика, 2008 7Li + 9Bе and 7Bе + 9Bе elastic scattering data at the energies Еlab(7Li) = 15.75, 24, 30, 34 МеV and Еlab(7Ве) = 17, 19 and 21 МеV were analyzed within the optical model and coupled-reaction-channels method taking into account 7Li, 7Bе and 9Bе ...
A. T. Rudchik +4 more
doaj
Asymptotic normalization coefficients and halo radii of 12B in the excited states
EPJ Web of Conferences, 2017 We present the results of measurements and analysis of the differential cross sections of the 11B(d, p)12B reaction leading to formation of the 1+ ground state and the 0.953-MeV 2+, 1.674-MeV 2−, 2.621-MeV 1−, 2.723-MeV 0+, 3.389-MeV 3− excited ...
Belyaeva T.L. +12 more
doaj +1 more source
Optimizing time and space MIMO antenna system for frequency selective fading channels [PDF]
, 2001 Smart or adaptive antennas promise to provide significant increases in system capacity and performance in wireless communication systems. In this paper, we investigate the use of adaptive antennas at the base and mobile stations, operating jointly, to ...
Letaief, KB, Murch, RD, Wong, KK
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source