Results 91 to 100 of about 338,910 (262)
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
We accurately analyze the $^6$He+$^{209}$Bi scattering at 19 and 22.5 MeV near the Coulomb barrier energy, using the continuum-discretized coupled-channels method (CDCC) based on the $n$+$n$+$^4$He+$^{209}$Bi four-body model.
K. Ogata +6 more
core +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Intercompartmental communication in senescence
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Energy dependence of the 13C + 16O scattering and quasi-molecular absorptian potential [PDF]
Experimental data of the 13С + 16O elastic scattering at the energies Еc.m.. = 6.28 - 59.17 MeV were analyzed within the optical model and coupled-reaction-channels method. The energy dependence for the 13С + 16O potential of the Woods - Saxon type with
A. T. Rudchik +4 more
doaj
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Elastic and inelastic scattering of 15N ions by 6Li nuclei at energy 81 MeV
Angular distributions of the elastic and inelastic scattering of 15N ions by 6Li nuclei were measured at the energy Elab(15N) = 81 MeV. The data were analyzed within the coupled-reaction-channels method (CRC).
A. T. Rudchik +17 more
doaj +1 more source
The cosmological 7Li problem from a nuclear physics perspective
The primordial abundance of 7Li as predicted by Big Bang Nucleosynthesis (BBN) is more than a factor 2 larger than what has been observed in metal-poor halo stars.
Broggini, C. +3 more
core +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source

