Results 31 to 40 of about 71,710 (221)

Cluster scattering in the non-local model

Frontiers in Physics, 2023
Scattering of weakly bound nuclei with a pronounced cluster structure is strongly affected by their breakup. Usually, this mechanism is accounted for in a three-body model with pairwise potentials.
N. K. Timofeyuk, M. Gómez-Ramos
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Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Elastic and inelastic scattering of 15n ions by 11B at 84 MeV [PDF]

Ядерна фізика та енергетика, 2014
Angular distributions of the 11B + 15N elastic and inelastic scattering were measured at Elab (15N) = 84 MeV. The data were analyzed within the optical model and coupled-reaction-channels method.
A. T. Rudchik, O. V. Herashchenko, K. A. Chercas, A. A. Rudchik, S. Kliczewski, Val. M. Pirnak, E. Piasecki, K. Rusek, A. Trczińska, S. B. Sakuta, R. Siudak, I. Strojek, A. Stolarz, E. I. Koshchy, A. O. Barabash, A. P. Ilyin, O. A. Ponkratenko, Yu. M. Stepanenko, V. V. Uleshchenko, Yu. O. Shyrma, J. Choiński, A. Szczurek   +21 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Energy dependence of the 6Li + 16O scattering and isotopic differences between potentials of the 6,7Li + 16O interactions [PDF]

Ядерна фізика та енергетика, 2012
Experimental data of the 6Li + 16O elastic scattering at Ec.m.. = 3.27 - 36.8 MeV known from literature, were analyzed within the optical model and coupled-reaction-channels method.
A. T. Rudchik,, R. M. Zelinskyi, V. A. Plujko, A. P. Ilyin, Val. M. Pirnak, O. A. Ponkratenko, A. A. Rudchik, V. V. Uleschenko   +7 more
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Elastic and inelastic scattering of 18O ions by 6Li at 114 MeV and isotopic differences of 6, 7Li + 18O and 6Li + 16, 18O nuclei interactions [PDF]

Ядерна фізика та енергетика, 2012
Angular distributions of the 6Li + 18O elastic and inelastic scattering as well as the 6Li(18O, Х) reactions with production of 16,17,19O + 8,7,5Li, 14,15,16,17N + 10,9,8,7Be and 12,13,14C + 12,11,10B nuclei were measured at Elab(18O) = = 114 MeV.
A. T. Rudchik, R. M. Zelinskyi, A. A. Rudchik, Val. M. Pirnak, S. Kliczewski, E. I. Koshchy, K. Rusek, V. A. Plujko, O. A. Ponkratenko, S. Yu. Mezhevych, A. P. Ilyin, V. V. Uleschenko, R. Siudak, J. Choiński, B. Czech, A. Szczurek   +15 more
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