Results 81 to 90 of about 682,008 (293)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Solution of fractional differential equations via coupled fixed point

open access: yesElectronic Journal of Differential Equations, 2015
In this article, we investigate the existence and uniqueness of a solution for the fractional differential equation by introducing some new coupled fixed point theorems for the class of mixed monotone operators with perturbations in the context of ...
Hojjat Afshari   +2 more
doaj  

Remarks on some coupled coincidence point results in partially ordered metric spaces

open access: yesArab Journal of Mathematical Sciences, 2014
In this paper we have used a method of reducing coupled coincidence and coupled fixed point results in partially ordered metric spaces to the respective results for mappings with one variable, even obtaining (in some cases) more general theorems.
Stojan Radenović
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Coupled Fixed Point Theorems for Weak Contraction Mappings under F-Invariant Set

open access: yesAbstract and Applied Analysis, 2012
We extend the recent results of the coupled fixed point theorems of Cho et al. (2012) by weakening the concept of the mixed monotone property. We also give some examples of a nonlinear contraction mapping, which is not applied to the existence of the ...
Wutiphol Sintunavarat   +2 more
doaj   +1 more source

Common coupled fixed point results in multiplicative metric spaces and applications

open access: yes, 2017
In the framework of a multiplicative metric space, by using the concept of w∗-compatible mappings, we establish some new common coupled fixed point theorems for two mappings satisfying φ-type contractive condition.
Yun Jiang, F. Gu
semanticscholar   +1 more source

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