The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
We investigate the chiral dynamics of gauge theories developing an infrared stable fixed point. We determine the dependence of the bilinear fermion condensate on the underlying fermion mass and its anomalous dimension.
A. Hietanen, Francesco Sannino
core +1 more source
Hybrid Coupled Fixed Point Theorems in Metric Spaces with Applications
In this manuscript, using CLR property, coupled coincidence and common coupled fixed point results for two-hybrid pairs satisfying (F,φ)- contraction are demonstrated.
M. Shoaib, M. Sarwar, T. Abdeljawad
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Fixed point results of weakly contraction mappings in partially ordered b-metric spaces
Objectives We explored the results of fixed point, coincidence point and coupled coincidence point for the mappings in an ordered metric spaces. Our results generalized and extended the well-known results in the literature.
K. Kalyani, N. Seshagiri Rao
doaj +1 more source
Infrared Fixed Points and Fixed Lines in the Top-Bottom-Tau Sector in Supersymmetric Grand Unification [PDF]
The two-loop ``top-down'' renormalization group flow for the top, bottom and tau Yukawa couplings is explored in the framework of supersymmetric grand unification; reproduction of the physical bottom and tau masses is required. Instead of following the recent trend of implementing exact Yukawa coupling unification i) a search for infrared (IR) fixed ...
arxiv +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Infra-red stable fixed points of R-parity violating Yukawa couplings in supersymmetric models [PDF]
We investigate the infra-red stable fixed points of the Yukawa couplings in the minimal version of the supersymmetric standard model with R-parity violation. Retaining only the R-parity violating couplings of higher generations, we analytically study the solutions of the renormalization group equations of these couplings together with the top- and b ...
arxiv +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
COUPLED FIXED POINT THEOREMS OF INTEGRAL TYPE MAPPINGS IN CONE METRIC SPACES [PDF]
In this paper, we prove some coupled fixed point theorems in cone metric spaces. Furthermore, we introduce and prove the integral version of coupled fixed point theorems in cone metric spaces.
Akewe, H, Okeke, G.A., Olaleru, J.O.
core