Results 81 to 90 of about 856,874 (305)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Coupled Fixed Point Theorems for Contraction Involving Rational Expressions in Partially Ordered Metric Spaces [PDF]
arXiv, 2010 We establish coupled fixed point theorems for contraction involving rational expressions in partially ordered metric spaces.
arxiv
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
The Method of Monotone Iterations for Mixed Monotone Operators in Partially Ordered Sets and Order-Attractive Fixed Points [PDF]
arXiv, 2013 We use the method of monotone iterations to obtain fixed point and coupled fixed point results for mixed monotone operators in the setting of partially ordered sets, with no additional assumptions on the partial order and with no convergence structure. We define the concept of attractive fixed point with respect to the partial order and obtain several ...
arxiv
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Coupled Models $WD_{3}$. Their Fixed Points
, 2001 7 pages, 6 figures, Proceedings of the conference "Statistical Field Theory", Como 2001.
Dotsenko, Vladimir S. +2 more
openaire +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Quadruple fixed point theorems for nonlinear contractions on partial metric spaces
Applied General Topology, 2014 The notion of coupled fixed point was introduced by Guo and Laksmikantham [12]. Later Gnana Bhaskar and Lakshmikantham in [11] investigated the coupled fixed points in the setting of partially ordered set by defining the notion of mixed monotone property.
Erdal Karapinar, Kenan Tas
doaj +1 more source
FG- coupled fixed point theorems for various contractions in partially ordered metric spaces [PDF]
arXiv, 2016 In this paper we introduce FG- coupled fixed point, which is a generalization of coupled fixed point for nonlinear mappings in partially ordered complete metric spaces. We discuss existence and uniqueness theorems of FG- coupled fixed points for different contractive mappings. Our theorems generalizes the results of Gnana Bhaskar and Lakshmikantham [T.
arxiv
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source